Estazolam Impurity 5 CAS CATO-C4X-19225
| CAS No. | CATO-C4X-19225 |
| Molecular Formula | C16H13ClN4O |
| Molecular Weight | 312.75 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Estazolam Impurity 5 (CAS CATO-C4X-19225, C16H13ClN4O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Estazolam Impurity 5 (C16H13ClN4O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Estazolam Impurity 5 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H13ClN4O |
| Molecular Weight | 312.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Estazolam Standards
Recommended Standards
- Erlotinib Impurity 13 (CAS 183322-18-1)
- Avatrombopag Impurity 4 (CAS 931395-73-2)
- 318238-06-1 KS-00001VO7 methyl 5-(4-chlorophenyl)-1-phenyl-1H-pyrazole-3-carboxylate (CAS 318238-06-1)
- Avatrombopag Impurity 74 (CAS CATO-C4X-223474)
- Ilaprazole Impurity 224 (CAS CATO-C4X-1130224)
- Perampanel Impurity 30 (CAS 1284376-94-8)
- Dacatavir lmpurity 37 (CAS 2077207-88-4)
- (2-Fluorophenyl)(3-(morpholinomethyl)phenyl)methanone (CAS 898791-92-9)
- 2-[(2,4-Dimethylphenyl)amino]-2-oxoethyl imidothiocarbamate hydrochloride (CAS 1047620-46-1)
- Bis(2-ethylhexyl) glutarate (CAS 21302-20-5)
- (R)-(3-Boc-amino)piperidine Hydrochloride (CAS 1217656-59-1)
- 2-Chloro-N4-cyclopentylpyrimidine-4,5-diamine (CAS 893728-35-3)
- 5-(1-(Tert-butoxycarbonyl)azetidin-3-yl)nicotinic acid (CAS 2095673-29-1)
- Semaglutide Impurity 21(HO-Ste-L-γGlu-AEEA-AEEA-OH) (CAS 1335440-44-2)
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