Droperidol Impurity 8 CAS 4644-61-5
| CAS No. | 4644-61-5 |
| Molecular Formula | C8H13NO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Droperidol Impurity 8 (CAS 4644-61-5), a pharmacopoeial impurity reference standard (molecular formula C8H13NO3HCl, MW 207.65 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Droperidol Impurity 8 (C8H13NO3HCl) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H13NO3 HCl |
| Molecular Weight | 207.65 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Droperidol Standards
- Droperidol EP Impurity B (CAS 1026015-45-1)
- Droperidol EP Impurity B HCl (CAS 1026015-45-1 (free base))
- Droperidol EP Impurity E (CAS 1346604-17-8)
- Droperidol EP Impurity E HCl (CAS 1346604-17-8 (free base))
- Droperidol EP Impurity A (CAS 2147-83-3)
- Droperidol Impurity 4 (CAS 25551-59-1)
- Droperidol Impurity 12 (CAS 3308-94-9)
- Droperidol Impurity 16 (CAS 39146-45-7)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com