6-Chloro-5-(3-(trifluoromethyl)phenyl)pyridine-2,4-diol CAS 477864-71-4
| CAS No. | 477864-71-4 |
| Molecular Formula | C12H7ClF3NO2 |
| Molecular Weight | 289.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 6-Chloro-5-(3-(trifluoromethyl)phenyl)pyridine-2,4-diol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
6-Chloro-5-(3-(trifluoromethyl)phenyl)pyridine-2,4-diol (CAS 477864-71-4) is a high-purity analytical reference standard with the molecular formula C12H7ClF3NO2 and a molecular weight of 289.64 g/mol.
6-Chloro-5-(3-(trifluoromethyl)phenyl)pyridine-2,4-diol (C12H7ClF3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H7ClF3NO2 |
| Molecular Weight | 289.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- Methyl 4-chloro-8-(trifluoromethyl)quinoline-2-carboxylate (CAS 1133115-62-4)
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- N2-(2-Chloro-5-(trifluoromethyl)phenyl)-1,3,5-triazine-2,4-diamine (CAS 175204-34-9)
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Recommended Standards
- 6-(Chloromethyl)-2-(5-(trifluoromethyl)pyridin-2-yl)pyrimidin-4-ol (CAS 266679-42-9)
- 6-Chloro-N-(4-(trifluoromethoxy)phenyl)pyrimidin-4-amine (CAS 714962-04-6)
- 5-Cyclopropyl-7-trifluoromethyl-pyrazolo-[1,5-a]pyrimidine-2-carbonyl chloride (CAS 861452-42-8)
- 8-methoxy-2-(trifluoromethyl)quinoline-5-carbonyl chloride (CAS 737740-52-2)
- N,N-Dimethyl-2-((1-(m-tolyl)isoquinolin-3-yl)oxy)ethanamine (CAS 89707-18-6)
- Ethyl 2-(1-{[1-(2-ethoxy-2-oxoethyl)cyclopropyl]amino}cyclopropyl)acetate (CAS 2007924-94-7)
- 2-(4-fluoro-5-methylfuran-3-yl)acetic acid (CAS 1513181-81-1)
- tert-Butyl methyl(pent-4-yn-1-yl)carbamate (CAS 1312304-14-5)
- (2R,3R,4S,5S,6R)-2-(((2S,3R,E)-2-Amino-3-hydroxyoctadec-4-en-1-yl)oxy)-6-(hydroxymethyl-13C)tetrahydro-2H-pyran-3,4,5-triol-2,3,4,5,6-13C5 (CAS 299172-48-8)
- 3'-Fluoro-[1,1'-biphenyl]-3-amine (CAS 400751-05-5)
- 5-(4-((4-Methylbenzyl)oxy)phenyl)-N'-(4-methylbenzylidene)-1H-pyrazole-3-carbohydrazide (CAS 634896-75-6)
- 4-Amino-5-(2-chlorobenzyl)-4H-1,2,4-triazole-3-thiol (CAS 151297-86-8)
- (3R)-5-CHLORO-2,3-DIHYDRO-1-BENZOFURAN-3-AMINE (CAS 1213380-80-3)
- Protein Kinase C (alpha) Peptide (CAS 159939-84-1)
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