6-Chloro-N-(4-(trifluoromethoxy)phenyl)pyrimidin-4-amine CAS 714962-04-6
| CAS No. | 714962-04-6 |
| Molecular Formula | C11H7ClF3N3O |
| Molecular Weight | 289.64 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Chloro-N-(4-(trifluoromethoxy)phenyl)pyrimidin-4-amine.
6-Chloro-N-(4-(trifluoromethoxy)phenyl)pyrimidin-4-amine (CAS 714962-04-6), molecular formula C11H7ClF3N3O and molecular weight 289.64 g/mol, is a CATO reference standard with documented purity and traceability.
6-Chloro-N-(4-(trifluoromethoxy)phenyl)pyrimidin-4-amine (C11H7ClF3N3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H7ClF3N3O |
| Molecular Weight | 289.64 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- Methyl 4-chloro-8-(trifluoromethyl)quinoline-2-carboxylate (CAS 1133115-62-4)
- 5-(2-Chloro-5-(trifluoromethyl)phenoxy)pyrazin-2-amine (CAS 1206970-21-9)
- Methyl 4-chloro-2-(trifluoromethyl)quinoline-3-carboxylate (CAS 1384264-57-6)
- 2-Chloro-1-[1-[3-(trifluoromethyl)phenyl]-1H-1,2,3-triazol-4-yl]ethanone (CAS 1384431-14-4)
- Methyl 4-chloro-7-(trifluoromethyl)quinoline-3-carboxylate (CAS 1448259-68-4)
- N2-(2-Chloro-5-(trifluoromethyl)phenyl)-1,3,5-triazine-2,4-diamine (CAS 175204-34-9)
- (E)-3-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-2-((E)-(methoxyimino)methyl)acrylonitrile (CAS 337919-85-4)
- 1-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)pyridin-4(1H)-one (CAS 866136-13-2)
Recommended Standards
- 6-Chloro-5-(3-(trifluoromethyl)phenyl)pyridine-2,4-diol (CAS 477864-71-4)
- 8-methoxy-2-(trifluoromethyl)quinoline-5-carbonyl chloride (CAS 737740-52-2)
- 6-(Chloromethyl)-2-(5-(trifluoromethyl)pyridin-2-yl)pyrimidin-4-ol (CAS 266679-42-9)
- Ethyl 4-chloro-6,7,8-trifluoroquinoline-3-carboxylate (CAS 207231-24-1)
- 7-Cyano-4-hydroxyquinoline-3-carboxylic acid (CAS 118078-26-5)
- 2-((5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)thio)acetic acid (CAS 40277-59-6)
- 1-(Tert-butyl) 4-methyl 4-(3-(trifluoromethyl)phenyl)piperidine-1,4-dicarboxylate (CAS 634466-24-3)
- 2-(Methoxymethyl)pyrimidine-4,6-diol (CAS 1903-90-8)
- 1-(But-3-en-1-yl)pyrrolidine (CAS 7255-63-2)
- Moctamide (CAS 29619-86-1)
- N-Methyl-3-(pyridin-4-yl)imidazo[1,2-a]pyrazin-8-amine (CAS 825630-38-4)
- Ethyl 2-amino-6-(2-hydroxyethyl)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate (CAS 36287-46-4)
- 6,6-Difluorospiro[3.3]Heptan-2-ol (CAS 2408974-56-9)
- Peptide 435 (CAS CATO-CPTD788435)
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