N-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(methoxyamino)methylene]thiourea CAS 477873-18-0
| CAS No. | 477873-18-0 |
| Molecular Formula | C9H8ClF3N4OS |
| Molecular Weight | 312.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 312.70 g/mol gives N-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(methoxyamino)methylene]thiourea distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(methoxyamino)methylene]thiourea (CAS 477873-18-0), molecular formula C9H8ClF3N4OS and molecular weight 312.70 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, N-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(methoxyamino)methylene]thiourea is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 312.70 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-N-[(methoxyamino)methylene]thiourea under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H8ClF3N4OS |
| Molecular Weight | 312.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 1-(4-Chlorophenyl)-3-(3-(difluoromethoxy)phenyl)urea (CAS 886542-48-9)
- 3-(4-Chlorophenyl)benzofuro[3,2-d]pyrimidine-2,4(1H,3H)-dione (CAS 121997-02-2)
- 1-(4-Chlorophenyl)-3-(3-(difluoromethoxy)phenyl)urea (CAS 540771-25-3)
- 5-(4-(5-Chlorobenzo[d]oxazol-2-yl)phenyl)-1,3,4-oxadiazol-2-amine (CAS 1706440-93-8)
- 1-(N-(2,2,2-Trifluoroethyl)sulfamoyl)piperidine-4-carboxylic acid (CAS 1183142-42-8)
- 1-Hydroxyethylidene-1,1-diphosphonic acid trisodium salt (CAS 2666-14-0)
- Methyl 4-(2-amino-4-chlorophenyl)butanoate (CAS 1188265-95-3)
- 1-Bromo-9,9-diphenyl-9H-fluorene (CAS 1547491-72-4)
- Propargylamine hydrochloride (CAS 15430-52-1)
- 2-(o-Tolyl)-1H-benzo[d]imidazole (CAS 2963-64-6)
- 3-(2,4-Dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)benzaldehyde (CAS 1261953-11-0)
- Ceftazidime Impurity 21 (CAS CATO-C4X-121221)
- 5-[2-(2-methylthiazol-4-yl)ethynyl]-1,2-benzoxazol-3-amine (CAS 2512322-46-0)
- Liraglutide Impurity 19 TFA Salt (CAS CATO-C4X-199219)
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