N-(3-chloro-2-methylphenyl)-3-(trifluoromethyl)benzamide CAS 478064-47-0
| CAS No. | 478064-47-0 |
| Molecular Formula | C15H11ClF3NO |
| Molecular Weight | 313.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N-(3-chloro-2-methylphenyl)-3-(trifluoromethyl)benzamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
N-(3-chloro-2-methylphenyl)-3-(trifluoromethyl)benzamide (CAS 478064-47-0), molecular formula C15H11ClF3NO and molecular weight 313.70 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, N-(3-chloro-2-methylphenyl)-3-(trifluoromethyl)benzamide (C15H11ClF3NO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 313.70 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-(3-chloro-2-methylphenyl)-3-(trifluoromethyl)benzamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H11ClF3NO |
| Molecular Weight | 313.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- N-(3-chlorobenzyl)-3-(trifluoromethyl)benzamide (CAS 303144-90-3)
- 2-(2,2,2-Trifluoroethylamino)-5-chlorobenzophenone (CAS 22753-80-6)
- N-(4-chlorophenyl)-N-methyl-3-(trifluoromethyl)benzamide (CAS 860649-45-2)
- 1-(4-Chlorophenyl)-3-((2,3,4-trifluorophenyl)amino)propan-1-one (CAS 868255-69-0)
- 2,5-Dibromo-2,3-dihydro-1H-inden-1-one (CAS 127425-72-3)
- 5-Chloropyrazolo[1,5-a]pyrimidine-3-carbaldehyde (CAS 1256162-94-3)
- N-(4-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}phenyl)-4-methoxybenzene-1-sulfonamide (CAS 478262-25-8)
- 5-(2-Nitrophenyl)furan-2-carboxylic Acid (CAS 29048-34-8)
- tert-Butyl (3S,5S)-3,5-bis(2,2,2-trifluoroethyl)piperazine-1-carboxylate (CAS 1260588-13-3)
- N-(2-Fluoro-4-(methylsulfonyl)phenyl)-6-(4-(3-isopropyl-1,2,4-oxadiazol-5-yl)piperidin-1-yl)-5-nitropyrimidin-4-amine (CAS 733750-99-7)
- Trimethylamine Hydrochloride (CAS 593-81-7)
- (2e)-3-{4-[(pyridin-3-yl)methoxy]phenyl}prop-2-enoic acid (CAS 227104-92-9)
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