1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-4-(4-nitrophenyl)piperazine CAS 478262-11-2
| CAS No. | 478262-11-2 |
| Molecular Formula | C16H14ClF3N4O2 |
| Molecular Weight | 386.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-4-(4-nitrophenyl)piperazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-4-(4-nitrophenyl)piperazine (CAS 478262-11-2), a certified reference material (molecular formula C16H14ClF3N4O2, MW 386.76 g/mol) for analytical method development and quality control.
1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-4-(4-nitrophenyl)piperazine (C16H14ClF3N4O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H14ClF3N4O2 |
| Molecular Weight | 386.76 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 4-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-[(ethylcarbamoyl)amino]benzamide (CAS 1092343-40-2)
- 4-((3-Chloro-4-fluorophenyl)amino)-7-ethoxy-6-nitroquinoline-3-carbonitrile (CAS 740791-06-4)
- 4-Chloro-3-[(2-methoxy-5-nitrophenyl)sulfamoyl]benzoic acid (CAS 327092-59-1)
- 5-(2-Chloro-4-(trifluoromethyl)phenoxy)-3-propoxyisobenzofuran-1(3H)-one (CAS 99199-20-9)
- 6-Chloro-4-ethyl-4-(4-fluorophenyl)-3-(2,2,2-trifluoroethyl)-3,4-dihydroquinazolin-2(1H)-one (CAS 910483-02-2)
- 3-Chloro-5-(trifluoromethyl)-2-(1-{[3-(trifluoromethyl)pyridin-2-yl]sulfanyl}ethyl)pyridine (CAS 1092345-94-2)
- 2-{[4-(4-chloro-2-fluorobenzenesulfonamido)phenyl]formamido}acetic acid (CAS 847751-79-5)
- 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-1-phenylpyrrolidine-2,5-dione (CAS 321430-83-5)
Recommended Standards
- 2,2,2-Trifluoroethyl (4-((4-chlorophenyl)carbamoyl)benzyl)carbamate (CAS 860649-84-9)
- 1,2,3,4,7,8-Hexachlorodibenzofuran 13C12 (CAS 114423-98-2)
- Lodoxamide lmpurity 15 (CAS 67605-91-8)
- Tert-butyl(2-chloro-4-fluoro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)dimethylsilane (CAS 1150561-59-3)
- 5-(Trifluoromethyl)-1,3-benzoxazol-2-amine hydrochloride (CAS 1820707-59-2)
- 2-tert-Butyloxycarbonylaminomethyl-5-p-tolyl-[1,3,4]oxadiazole (CAS 1053656-58-8)
- 4-Bromo-7-methoxyisoindolin-1-one (CAS 808127-82-4)
- N-{4-[(6-{4-[(1R)-1-(4-fluorophenyl)ethyl]piperazin-1-yl}pyrimidin-4-yl)oxy]-1,3-benzothiazol-2-yl}acetamide (CAS 862269-93-0)
- 2,5-Dibromo-n-(thiophen-2-ylmethyl)benzenesulfonamide (CAS 848336-24-3)
- (2S,3R,5R)-3-(Hydroxymethyl)-3-methyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide (CAS 95123-10-7)
- 5-Methyl-7-(piperazin-1-yl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 892253-50-8)
- N-(2-Ethoxyphenyl)-3-(4-hydroxy-3-methoxyphenyl)-2-(2H-1,2,3,4-tetrazol-5-yl)propanamide (CAS 483995-87-5)
- 68881-66-3 Azepane-1-carbothioamide DTXSID30499185 (CAS 68881-66-3)
- Semaglutide impurity 211 (CAS CATO-C4X-2226211)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com