Rebamipide Impurity 8 CAS 4876-14-6
| CAS No. | 4876-14-6 |
| Molecular Formula | C12H12N2O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Rebamipide Impurity 8 is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Rebamipide Impurity 8 (CAS 4876-14-6), a pharmacopoeial impurity reference standard (molecular formula C12H12N2O3HCl, MW 268.70 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Rebamipide Impurity 8 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 268.70 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Rebamipide Impurity 8 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H12N2O3 HCl |
| Molecular Weight | 268.70 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Rebamipide Standards
- Rebamipide Impurity 4 (CAS 100342-53-8)
- Rebamipide impurity 25 (CAS 1022283-52-8)
- Rebamipide Impurity 43 (CAS 1028268-32-7)
- Rebamipide impurity 20 (CAS 1205-74-9)
- Rebamipide-d4 (CAS 1219409-06-9)
- Rebamipide Impurity 12 (CAS 132210-24-3)
- Rebamipide Impurity 60 (CAS 135252-30-1)
- Rebamipide impurity 02 (CAS 1984832-92-9)
Recommended Standards
- Avibactam Impurity 36 (CAS CATO-C4X-134836)
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- Epinephrine /Adrenaline Impurity 115 (CAS CATO-C4X-1849115)
- (5-(tert-Butyl)oxazol-2-yl)methanol (CAS 252662-39-8)
- 3-amino-1-methyl-azepan-2-one;hydrochloride (CAS 2197418-37-2)
- 4-Bromo-2-cyclopropylpyridine (CAS 1086381-28-3)
- 6-Chloro-2,3-difluorobenzeneethanol (CAS 887585-49-1)
- Methyl 4-bromo-8-fluoroquinoline-2-carboxylate (CAS 1314141-67-7)
- N-hydroxy-1-methyl-1H-indazole-5-carbimidoyl chloride (CAS 1956426-70-2)
- Anti-TF Antigen Peptide P30-1 trifluoroacetate salt (CAS 573664-50-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com