Betahistine Impurity 22 CAS 49745-42-8
| CAS No. | 49745-42-8 |
| Molecular Formula | C8H11NO2 |
| Molecular Weight | 153.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 153.18 g/mol gives Betahistine Impurity 22 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Betahistine Impurity 22 (CAS 49745-42-8), a pharmacopoeial impurity reference standard (molecular formula C8H11NO2, MW 153.18 g/mol) used for the identification and quantification of trace impurities in APIs.
Betahistine Impurity 22 (C8H11NO2) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Betahistine Impurity 22 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H11NO2 |
| Molecular Weight | 153.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Nitrogen Atoms | 1 |
Related Betahistine Standards
- Betahistine impurity N3 (CAS 562101-24-0)
- Betahistine impurity 33 (CAS 13585-92-7)
- Betahistine impurity 41 (CAS 113985-59-4)
- Betahistine Impurity 27 (CAS 26832-29-1)
- Betahistine Impurity 03 (CAS 88780-61-4)
- Betahistine Impurity 19 (CAS 32635-81-7)
- Betahistine impurity 37 (CAS CATO-C4X-183837)
- Betahistine impurity 38 (CAS CATO-C4X-183838)
Recommended Standards
- Miglitol Impurity 8 (CAS CATO-C4X-16978)
- 2-hydroxyethyl-6-hydroxymethylpyridine (CAS CATO-C4X-183851)
- Miglitol impurity 23 (CAS 1824614-40-5)
- Pyridoxine /Vitamin B6 Impurity 34 (CAS 4811-03-4)
- Vonoprazan Impurity 192(Mixture of Z and E Isomers) (CAS CATO-C4X-1020192)
- Tetrabenazine Impurity 34 (CAS CATO-C4X-274834)
- Epirubicin Impurity 12 (CAS CATO-C4X-111612)
- 5,6,7-Trimethoxy-4-methyl-2H-chromen-2-one (CAS 7679-43-8)
- 2-(Benzyloxy)-4-bromoaniline (CAS 495406-90-1)
- 6-ethyl-1H,2H,3H,4H-thieno[2,3-d]pyrimidine-2,4-dione (CAS 502649-08-3)
- (R)-2-Amino-8-methyl-7,8-dihydro-5H-pyrano[4,3-b]pyridin-5-one (CAS 2673370-67-5)
- Dichlorobis(3,7-diacetyl-1,3,7-triaza-5-phosphabicyclo[3.3.1]nonane) palladium(II) (CAS 1248347-61-6)
- 5-Bromo-7-methoxy-1H-indole (CAS 938061-47-3)
- Glucagon receptor antagonists-2 (CAS 202917-18-8)
Why CATO?
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