Vonoprazan Impurity 192(Mixture of Z and E Isomers) CAS CATO-C4X-1020192
| CAS No. | CATO-C4X-1020192 |
| Molecular Formula | C5H8N2O5 |
| Molecular Weight | 176.13 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Vonoprazan Impurity 192(Mixture of Z and E Isomers) (CAS CATO-C4X-1020192), a pharmacopoeial impurity reference standard (molecular formula C5H8N2O5, MW 176.13 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Vonoprazan Impurity 192(Mixture of Z and E Isomers) (C5H8N2O5) is characterized by a carbohydrate-derived structure, an amide group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C5H8N2O5 |
| Molecular Weight | 176.13 g/mol |
| Appearance | White to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| Nitrogen Atoms | 2 |
Related Vonoprazan Standards
- Vonoprazan Impurity 200 (CAS CATO-C4X-1020200)
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Recommended Standards
- Allantoicacid (CAS 99-16-1)
- 2-Nitrosoisoindoline-1,3-dione (CAS 364745-13-1)
- Daprodustat Impurity 33 (CAS CATO-C4X-240733)
- Isochromane-1,3,4-trione (CAS 6328-17-2)
- Empagliflozin Impurity 293 (CAS 1185339-44-9)
- Levofloxacin Impurity 47 (CAS 110548-06-6)
- Estazolam Impurity 1 (CAS CATO-C4X-19221)
- 2-[4-(4-Chloro-2-fluorophenoxy)phenyl]-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane (CAS 1426337-41-8)
- 1-(p-Tolyl)dodecan-1-one (CAS 50671-19-7)
- N2-Nitroso Levomefolic Acid (CAS CATO-C4X-139549)
- 3-Cyclopentylpropionyl Chloride (CAS 104-97-2)
- N-ethyl-2-methoxyaniline (CAS 15258-43-2)
- tert-Butyl7-fluoro-1,2,3,5-tetrahydro-4H-benzo[e][1,4]diazepine-4-carboxylate (CAS 886364-36-9)
- Semaglutide impurity 289 (CAS CATO-C4X-2226289)
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