Rapamycin Impurity 9 CAS 500733-49-3
| CAS No. | 500733-49-3 |
| Molecular Formula | C51H79NO15 |
| Molecular Weight | 946.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Rapamycin Impurity 9 (C51H79NO15) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Rapamycin Impurity 9 (CAS 500733-49-3, C51H79NO15) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Rapamycin Impurity 9 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C51H79NO15 |
| Molecular Weight | 946.17 g/mol |
| Purity | Technical Grade |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Nitrogen Atoms | 1 |
Related Rapamycin Standards
- Rapamycin Impurity 22 (CAS 185107-79-3)
- Rapamycin Impurity 32 (CAS CATO-C4X-174632)
- Rapamycin Impurity 10 (CAS 157054-84-7)
- Rapamycin Impurity 11 (CAS 159351-88-9)
- 33-Ethyl Rapamycin (CAS CATO-C4X-174617)
- Rapamycin Impurity 23 (CAS CATO-C4X-174623)
- Rapamycin Impurity 8 (CAS CATO-C4X-17468)
- Rapamycin Impurity 12 (CAS 150821-39-9)
Recommended Standards
- Vinfosiltine (CAS 123286-00-0)
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- Docetaxel Impurity 76 (CAS CATO-C4X-161976)
- 144765-80-0 b-D-Glucopyranoside,2-(3,4-dimethoxyphenyl)ethyl 3-O-(2,3,4-tri-O-acetyl-6-deoxy-a-L-mannopyranosyl)-,2,6-diacetate 4-[3-[3,4-bis(acetyloxy)phenyl]-2-propenoate], (E)- (9CI) (CAS 144765-80-0)
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- Ceftriaxone Impurity 37 (CAS 149-30-4)
- Atrasentan Impurity 158 (CAS 2469258-87-3)
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- 2-(1-Amino-3-methylcyclopentyl)acetic acid (CAS 1342502-37-7)
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- 2-Chloro-4-(4-chloro-2-methoxyphenyl)benzonitrile (CAS 1355248-21-3)
- 4-Amino-6-MethoxyPyrimidine 6-methoxypyrimidin-4-amine 696-45-7 A9213 (CAS 696-45-7)
- Fragment-[7-31]-Liraglutide (CAS CATO-C4X-199239)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com