Metoprolol EP Impurity G CAS 501-94-0

Description

Compared with other compounds in its class, the molecular weight of 138.16 g/mol gives Metoprolol EP Impurity G distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Metoprolol EP Impurity G (CAS 501-94-0), a pharmacopoeial impurity reference standard (molecular formula C8H10O2, MW 138.16 g/mol) used for the identification and quantification of trace impurities in APIs.

Based on its molecular formula C8H10O2, Metoprolol EP Impurity G contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 138.16 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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