Metoprolol Impurity 23 CAS 330976-39-1
| CAS No. | 330976-39-1 |
| Molecular Formula | C9H12O2 |
| Molecular Weight | 152.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Metoprolol Impurity 23.
As a process- or degradation-related impurity, Metoprolol Impurity 23 (CAS 330976-39-1, C9H12O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, Metoprolol Impurity 23 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 152.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Metoprolol Impurity 23 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H12O2 |
| Molecular Weight | 152.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
Related Metoprolol Standards
- Metoprolol Impurity 12 (CAS 32846-01-8)
- Metoprolol EP Impurity B (CAS 56718-71-9)
- Metoprolol Process Impurity 4 (CAS 84803-56-5)
- Metoprolol EP Impurity G (CAS 501-94-0)
- Metoprolol EP Impurity N (CAS 6452-57-9)
- Metoprolol Impurity 31 (CAS 942499-01-6)
- Metoprolol Impurity 37 (CAS 488-17-5)
- Metoprolol Impurity 26 (CAS 69628-98-4)
Recommended Standards
- Rivastigmine EP Impurity G (CAS 23308-82-9)
- Umeclidinium impurity 23 (CAS 622-08-2)
- Dapoxetine Impurity 86 (CAS 103548-16-9)
- Pregabalin Impurity 66 (CAS 143420-53-5)
- Promestriene Impurity 14 (CAS CATO-C4X-220514)
- Lemborexant Impurity 35 (CAS CATO-C4X-304235)
- Prednisolone Impurity 20 (CAS CATO-C4X-173720)
- 6-Phenoxypyrimidin-4-amine (CAS 90946-08-0)
- 6-Bromo-2-fluoro-3-iodobenzonitrile (CAS 217816-65-4)
- (6-Fluoro-4-nitropyridin-2-yl)methanamine (CAS 1393554-83-0)
- N,N'-(((((4-(tert-butyl)phenyl)sulfonyl)azanediyl)bis(methylene))bis(3,1-phenylene))diacetamide (CAS 866155-45-5)
- Methyl 3-bromo-1H-pyrazole-5-carboxylate (CAS 2246373-43-1)
- Dobutamine EP Impurity C HCl (CAS 51062-14-7)
- Semaglutide impurity 201 (CAS CATO-C4X-2226201)
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