Tenofovir Alafenamide Impurity 48 CAS 50615-40-2
| CAS No. | 50615-40-2 |
| Molecular Formula | C8H10ClN5 |
| Molecular Weight | 211.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Tenofovir Alafenamide Impurity 48 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Tenofovir Alafenamide Impurity 48 (CAS 50615-40-2), a pharmacopoeial impurity reference standard (molecular formula C8H10ClN5, MW 211.65 g/mol) used for the identification and quantification of trace impurities in APIs.
Tenofovir Alafenamide Impurity 48 (C8H10ClN5) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C8H10ClN5 |
| Molecular Weight | 211.65 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Tenofovir Standards
- Tenofovir disoproxil Impurity 78 (CAS CATO-C4X-107678)
- Tenofovir disoproxil Impurity 142 (CAS 102537-97-3)
- Tenofovir disoproxil Impurity 143 (CAS CATO-C4X-1076143)
- Tenofovir disoproxil Impurity 89 (CAS 2307-69-9)
- Tenofovir disoproxil Impurity 88 (CAS 80-40-0)
- Tenofovir alafenamide impurity 85 (CAS 121149-98-2)
- Tenofovir alafenamide impurity N1 (CAS 16958-60-4)
- Tenofovir Impurity 110 (CAS 20776-34-5)
Recommended Standards
- Suvorexant Impurity 9 (CAS 2762965-06-8)
- N'-(6-chloropyridin-2-yl)cyclopropanecarbohydrazide (CAS 478064-08-3)
- Guanfacine Hydrochloride Impurity 4 (CAS 57486-36-9)
- N-(3-Chlorophenyl)-N-(diaminomethylene)guanidine (CAS 48144-44-1)
- Ceftazidime Impurity 46 (CAS 134203-50-2)
- Bevantolol Impurity 18 (CAS CATO-C4X-241118)
- Ambroxol Impurity 101 (CAS CATO-C4X-1085101)
- tert-Butyl (4-fluoro-4-(hydroxymethyl)cyclohexyl)carbamate (CAS 1374654-57-5)
- 10-Methyl-9-oxo-9,10-dihydroacridine-1,3-diyl diacetate (CAS 28333-08-6)
- (s)-3-Amino-3-(pyridin-2-yl)propanoic acid (CAS 149196-85-0)
- 3-Morpholino-5-(trifluoromethyl)aniline (CAS 641571-02-0)
- Probucol Impurity 17 (CAS 1195639-22-5)
- KH CB19 (CAS 1354037-26-5)
- Semaglutide Impurity 192 (CAS CATO-C4X-2226192)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com