Tamoxifen EP Impurity G HCl CAS 94911-67-8
| CAS No. | 94911-67-8 |
| Molecular Formula | C20H25NO2 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Tamoxifen EP Impurity G HCl (CAS 94911-67-8, C20H25NO2HCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C20H25NO2HCl, Tamoxifen EP Impurity G HCl contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 347.88 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H25NO2 HCl |
| Molecular Weight | 347.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Tamoxifen Standards
- Tamoxifen (CAS 10540-29-1)
- Tamoxifen Citrate Impurity 25 (CAS 114828-90-9)
- Tamoxifen Impurity 18 (CAS 123091-15-6)
- Tamoxifen EP Impurity A (CAS 13002-65-8)
- Tamoxifen Dimer (CAS 1346606-51-6)
- Tamoxifen Impurity 15 (CAS 157698-32-3)
- Tamoxifen Citrate EP Impurity D Hydrochloride(E-Isomer) (CAS 15917-51-8)
- Tamoxifen EP Impurity F HCl (CAS 15917-65-4)
Recommended Standards
- Crisaborole Impurity 48 (CAS 22532-61-2)
- Indacaterol Impurity 11 (CAS CATO-C4X-150011)
- Dronedarone Impurity 74 (CAS 948015-51-8)
- 2-{4-[(difluoromethyl)sulfanyl]-3-methoxyphenyl}acetonitrile (CAS 1269151-40-7)
- 2-[4-[2-(4,5-Dihydro-4,4-dimethyl-2-oxazolyl)-1-naphthalenyl]phenyl]-4,5-dihydro-4,4-dimethyloxazole (CAS 85678-98-4)
- N,5-Dimethoxy-N,2-dimethylnicotinamide (CAS 1211538-30-5)
- 1,3-Bis(1,3-dimethyl-1h-pyrazol-4-yl)propane-1,3-dione (CAS 1006356-08-6)
- 6-Hydroxy-1-phenyl-1,4-dihydro-5H-pyrazolo[4,3-d]pyrimidine-5,7(6H)-dione (CAS 16078-72-1)
- Quality Control Sample MIX 11 (CAS CATO-LINS001240)
- Peptide 46 (H-4054.0500) (CAS 192122-40-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com