Pralatrexate Impurity 2 CAS 52454-37-2
| CAS No. | 52454-37-2 |
| Molecular Formula | C20H21N7O5 |
| Molecular Weight | 439.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Pralatrexate Impurity 2 (CAS 52454-37-2), a certified reference material (molecular formula C20H21N7O5, MW 439.42 g/mol) for analytical method development and quality control.
Structurally, Pralatrexate Impurity 2 (C20H21N7O5) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 439.42 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Pralatrexate Impurity 2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H21N7O5 |
| Molecular Weight | 439.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1971 |
| Nitrogen Atoms | 7 |
Related Pralatrexate Standards
- Pralatrexate-D5 (CAS 146464-95-1)
- R-Pralatrexate (CAS 1320211-70-8)
- S-Pralatrexate (CAS 1320211-69-5)
- Pralatrexate Impurity 3 (CAS CATO-C4X-22143)
- Pralatrexate Impurity 8 (CAS 374777-77-2)
- Pralatrexate Impurity 4 (CAS 146464-93-9)
- Pralatrexate Impurity 2 (CAS 2028268-08-6)
- Pralatrexate Impurity 1 (CAS 716-74-5)
Recommended Standards
- N-(3-(((4-fluorobenzyl)oxy)methyl)phenyl)-4-(trifluoromethyl)benzenesulfonamide (CAS 338392-94-2)
- Rivaroxaban Impurity 117 (CAS CATO-C4X-1090117)
- Ethyl 2-cyano-3-(3-methoxy-4-(2-((2-methyl-5-nitrophenyl)amino)-2-oxoethoxy)phenyl)acrylate (CAS 334497-35-7)
- Rivaroxaban Impurity 27 (CAS 1365267-37-3)
- N-Formyl 2-chloro-5-trifluoromethylaniline (CAS 657-63-6)
- (e)-3-(2-(Pyridin-2-yl)hydrazono)azepan-2-one (CAS 49837-11-8)
- Glyceryl Eicosapentaenoic acid (CAS CATO-C4X-289021)
- (S)-2-((S)-2-(2-Aminoacetamido)-3-(1H-imidazol-4-yl)propanamido)-3-(1H-imidazol-4-yl)propanoic acid (CAS 106644-04-6)
- 1-(Furan-3-yl)prop-2-en-1-amine (CAS 1270486-60-6)
- 3-Methyl-1-(pyridin-2-ylmethyl)-1h-pyrazole-5-carboxylic acid (CAS 1522841-47-9)
- 4-(5-Ethyl-benzooxazol-2-yl)-phenylamine (CAS 328908-02-7)
- 4-Hydroxyindoline-2,3-dione (CAS 116569-10-9)
- Ethyl 2-amino-4-methylpent-4-enoate (CAS 68843-73-2)
- Semaglutide impurity 256 (CAS CATO-C4X-2226256)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com