Pralatrexate Impurity 4 CAS 146464-93-9
| CAS No. | 146464-93-9 |
| Molecular Formula | C18H16N6O2 |
| Molecular Weight | 348.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Pralatrexate Impurity 4 (CAS 146464-93-9), a pharmacopoeial impurity reference standard (molecular formula C18H16N6O2, MW 348.36 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Pralatrexate Impurity 4 (C18H16N6O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 14.0, corresponding to approximately 14 ring(s) or double-bond equivalent(s). With a molecular weight of 348.36 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Pralatrexate Impurity 4 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H16N6O2 |
| Molecular Weight | 348.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 6 |
Related Pralatrexate Standards
- Pralatrexate Impurity 2 (CAS 2028268-08-6)
- Pralatrexate Impurity 2 (CAS 52454-37-2)
- Pralatrexate-D5 (CAS 146464-95-1)
- R-Pralatrexate (CAS 1320211-70-8)
- S-Pralatrexate (CAS 1320211-69-5)
- Pralatrexate Impurity 3 (CAS CATO-C4X-22143)
- Pralatrexate Impurity 1 (CAS 716-74-5)
- Pralatrexate Impurity 8 (CAS 374777-77-2)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com