Betamethasone Enol Aldehyde Z Isomer CAS 52647-06-0
| CAS No. | 52647-06-0 |
| Molecular Formula | C22H27FO4 |
| Molecular Weight | 374.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Betamethasone Enol Aldehyde Z Isomer (CAS 52647-06-0), molecular formula C22H27FO4 and molecular weight 374.45 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution, Betamethasone Enol Aldehyde Z Isomer is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 374.45 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Betamethasone Enol Aldehyde Z Isomer meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H27FO4 |
| Molecular Weight | 374.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | F-containing |
Related Betamethasone Standards
- Betamethasone-delta17,20 21-Aldehyde (Mixture of Isomers) (CAS 6762-45-4)
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Recommended Standards
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- Dexamethasone Impurity 23 (CAS 59860-99-0)
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