Dexamethasone Impurity 39 CAS 6762-51-2
| CAS No. | 6762-51-2 |
| Molecular Formula | C22H27FO4 |
| Molecular Weight | 374.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Dexamethasone Impurity 39 (C22H27FO4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Dexamethasone Impurity 39 (CAS 6762-51-2, C22H27FO4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Dexamethasone Impurity 39 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H27FO4 |
| Molecular Weight | 374.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | F-containing |
Related Dexamethasone Standards
- Dexamethasone Oxetanone (CAS 4089-36-5)
- Dexamethasone Impurity 104 (CAS 62800-49-1)
- Dexamethasone Impurity 120 (CAS CATO-C4X-1165120)
- Dexamethasone Impurity 23 (CAS 59860-99-0)
- Dexamethasone Impurity 95 (CAS CATO-C4X-116595)
- Dexamethasone Desfluoro 11-Epimer (CAS 78761-59-8)
- Dexamethasone EP Impurity J (CAS 2036-77-3)
- Dexamethasone EP Impurity D (CAS 24916-90-3)
Recommended Standards
- Betamethasone Enol Aldehyde Z Isomer (CAS 52647-06-0)
- Betamethasone Enol Aldehyde E Isomer (CAS 52647-07-1)
- Donepezil EP impurity E (CAS CATO-C4X-103936)
- Clobetasol Propionate EP Impurity F (CAS 2412496-00-3)
- Brexpiprazole Impurity 113 (CAS 105685-06-1)
- Itopride Impurity 27 (CAS CATO-C4X-137727)
- Lactic acid impurity 2 (CAS 1823698-42-5)
- Cis-1,4-Bis-(Methylsulfonyloxy)-But-2-Ene (CAS 2303-47-1)
- Alcian Blue, pyridine variant (CAS 123439-83-8)
- Formaldehyde Sodium Bisulfite Hemihydrate (CAS 63148-74-3)
- 6-Methoxynicotinohydrazide (CAS 89853-74-7)
- 6-Fluoro-4-hydroxy-2-methyl-3-nitroquinoline (CAS 1203578-88-4)
- Ethyl 2-(trifluoromethyl)piperazine-1-carboxylate (CAS 1123515-55-8)
- (Tyr?)-C-Type Natriuretic Peptide (32-53) (human, porcine, rat) (CAS 142878-79-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com