Metoclopramide Impurity 41 CAS 52702-04-2
| CAS No. | 52702-04-2 |
| Molecular Formula | C10H14ClN3O2 |
| Molecular Weight | 243.69 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Metoclopramide Impurity 41 (C10H14ClN3O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Metoclopramide Impurity 41 (CAS 52702-04-2), a pharmacopoeial impurity reference standard (molecular formula C10H14ClN3O2, MW 243.69 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H14ClN3O2 |
| Molecular Weight | 243.69 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Metoclopramide Standards
- Metoclopramide Impurity 88 (CAS CATO-C4X-141588)
- Metoclopramide Impurity 12 (CAS 24201-13-6)
- Metoclopramide impurity 78 (CAS CATO-C4X-141578)
- Metoclopramide Impurity 99 (CAS CATO-C4X-141599)
- Metoclopramide Impurity 119 (CAS CATO-C4X-1415119)
- Metoclopramide Impurity 89 (CAS CATO-C4X-141589)
- Metoclopramide Impurity 86 (CAS CATO-C4X-141586)
- Metoclopramide Impurity 84 (CAS 2486-67-1)
Recommended Standards
- Apixaban Impurity 141 (CAS CATO-C4X-1088141)
- Mosapride Impurity 43 (CAS 1225199-36-9)
- Loratadine EP Impurity B (CAS 31251-41-9)
- 65836-72-8 Acetamide, 2-chloro-N-((3,4-dimethoxyphenyl)methyl)- 3-13-00-02189 (Beilstein Handbook Reference) BRN 2857211 2-Chloro-N-((3,4-dimethoxyphenyl)methyl)acetamide N-(Dimethoxy-3,4 benzyl)-chloroacetamide [French] N-(Dimethoxy-3,4 benzyl)-chloroacetamide (CAS 65836-72-8)
- Josamycin EP Impurity B (18-Dihydroleucomycin A3) (CAS 40361-41-9)
- Esmolol Impurity N1 (CAS 50666-68-7)
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- N-(4-Fluorobenzyl)-1-naphthalenamine (CAS 356531-44-7)
- Loxoprofen impurity 98 (CAS CATO-C4X-148898)
- 3-Amino-3-(1-phenyl-1h-pyrazol-4-yl)propan-1-ol (CAS 1248671-16-0)
- 1,1,1,2,4,4,5,7,7,8,10,10,11,13,13,14,16,16,17,17,18,18,18-Tricosafluoro-5,8,11,14-tetrakis(trifluoromethyl)-3,6,9,12,15-pentaoxaoctadecane (CAS 37486-69-4)
- Liraglutide Impurity 22 (CAS 536721-25-2)
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