Loratadine EP Impurity B CAS 31251-41-9
| CAS No. | 31251-41-9 |
| Molecular Formula | C14H10ClNO |
| Molecular Weight | 243.69 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Loratadine EP Impurity B meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Loratadine EP Impurity B (CAS 31251-41-9) is a certified pharmaceutical impurity reference standard with the molecular formula C14H10ClNO and a molecular weight of 243.69 g/mol.
Based on its molecular formula C14H10ClNO, Loratadine EP Impurity B contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 243.69 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C14H10ClNO |
| Molecular Weight | 243.69 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1965 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Loratadine Standards
- Loratadine impurity 85 (CAS 3964-84-9)
- Loratadine impurity 86 (CAS 31251-43-1)
- Loratadine Impurity 18 (CAS 31255-57-9)
- Loratadine Impurity 74 (CAS 31255-58-0)
- Loratadine Impurity 90 (CAS 133330-72-0)
- Loratadine Impurity 31 (CAS 31255-47-7)
- Loratadine Impurity B (CAS 38093-12-8)
- Loratadine Impurity 68 (CAS 133345-21-8)
Recommended Standards
- Metoclopramide Impurity 88 (CAS CATO-C4X-141588)
- Metoclopramide Impurity 41 (CAS 52702-04-2)
- Apixaban Impurity 141 (CAS CATO-C4X-1088141)
- Atenolol EP Impurity D (CAS 115538-83-5)
- Picosulfate Impurity 33 (CAS CATO-C4X-123733)
- Halometasone impurity 16 (CAS CATO-C4X-144616)
- Upadacitinib Impurity 80 2HCl (CAS CATO-C4X-240580)
- Fluorescent Brightener 264 (Technical Grade) (CAS 68971-49-3)
- 4-[2-(2-Methoxy-phenyl)-ethyl]-piperidine 654662-91-6 7491AE C14H21NO (CAS 654662-91-6)
- 1-(4-methoxyphenyl)-3-methyl-6-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 1011397-71-9)
- 2-{[(Butan-2-yl)amino]methyl}phenol hydrochloride (CAS 855350-91-3)
- 6,8-Dichloro-2-oxo-2H-chromene-3-carboxamide (CAS 101166-95-4)
- 5-Amino-1-benzyl-N-(4-methoxyphenyl)-1H-1,2,3-triazole-4-carboxamide (CAS 361367-39-7)
- Des-Pro-Pro-Tirzepatide (CAS CATO-CPTD788696)
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