Tranexamic Impurity 19 CAS 5278-91-1
| CAS No. | 5278-91-1 |
| Molecular Formula | C8H6Cl2O2 |
| Molecular Weight | 205.04 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Tranexamic Impurity 19 (CAS 5278-91-1), a pharmacopoeial impurity reference standard (molecular formula C8H6Cl2O2, MW 205.04 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Tranexamic Impurity 19 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 205.04 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Tranexamic Impurity 19 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H6Cl2O2 |
| Molecular Weight | 205.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
Related Tranexamic Standards
- Tranexamic Impurity 21 (CAS 195370-52-6)
- Tranexamic Impurity 39 (CAS CATO-C4X-177139)
- Tranexamic Acid Impurity 18 (CAS 10473-24-2)
- Tranexamic Acid Impurity 10 (CAS CATO-C4X-177110)
- Tranexamic Impurity 38 (CAS CATO-C4X-177138)
- Tranexamic Impurity 26 (CAS CATO-C4X-177126)
- Tranexamic Impurity 29 (CAS CATO-C4X-177129)
- Tranexamic Impurity 25 (CAS CATO-C4X-177125)
Recommended Standards
- Econazole Impurity 4 (CAS 137958-96-4)
- Guanfacine Hydrochloride Impurity 3 (CAS 6575-24-2)
- Regorafenib Impurity 65 (CAS 1403469-80-6)
- Revefenacin Impurity 113 (CAS 1379371-59-1)
- Idebenone Impurity 11 (CAS 116460-81-2)
- Ezetimibe Impurity 82 (CAS CATO-C4X-109882)
- Edoxaban Impurity 20 (CAS 1210348-34-7)
- 5-Bromo-1-methylpyridin-2(1H)-one (CAS 81971-39-3)
- Methyl 4-isopropylpiperidine-4-carboxylate hydrochloride (CAS 2470439-99-5)
- N'-hydroxy-4-(oxazol-5-yl)benzimidamide (CAS 860649-01-0)
- 5-Amino-3-(thiophen-3-yl)pentan-1-ol (CAS 1447966-96-2)
- 4-(Thiophen-2-ylmethyl)benzonitrile (CAS 100005-79-6)
- Ethyl 4-(2,6-Difluorophenyl)-2-Hydroxy-4-Oxobut-2-Enoate (CAS 1342259-34-0)
- (Tyr?)-C-Type Natriuretic Peptide (32-53) (human, porcine, rat) (CAS 142878-79-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com