Lemborexant impurity 4 CAS 528587-70-4
| CAS No. | 528587-70-4 |
| Molecular Formula | C11H9FO2 |
| Molecular Weight | 192.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Lemborexant impurity 4 is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Lemborexant impurity 4 (CAS 528587-70-4) is a certified pharmaceutical impurity reference standard with the molecular formula C11H9FO2 and a molecular weight of 192.19 g/mol.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, Lemborexant impurity 4 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 192.19 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Lemborexant impurity 4 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H9FO2 |
| Molecular Weight | 192.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | F-containing |
Related Lemborexant Standards
- Lemborexant Impurity 53 (CAS CATO-C4X-304253)
- Lemborexant Impurity 61 (CAS 528587-69-1)
- Lemborexant Impurity 62 (CAS CATO-C4X-304262)
- Lemborexant Impurity 75 (CAS 2412536-16-2)
- Lemborexant Impurity 92 (CAS CATO-C4X-304292)
- Lemborexant Impurity 93 (CAS CATO-C4X-304293)
- Lemborexant impurity 3 (CAS 571189-49-6)
- Lemborexant Impurity 38 (CAS 1450904-98-9)
Recommended Standards
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- 335081-02-2 N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-(13C3)alanine (CAS 335081-02-2)
- Lasmiditan Impurity 6 (CAS 28314-80-9)
- Amoxicillin Impurity 46 (CAS CATO-C4X-114846)
- Empagliflozin Impurity 280 (CAS 2562349-63-5)
- N-(4-(4-oxo-2-thioxo-1,4-dihydroquinazolin-3(2H)-yl)phenyl)acetamide (CAS 497060-21-6)
- 2-(N-(4-fluorophenyl)methylsulfonamido)butanoic acid (CAS 1218095-70-5)
- 4-Fluoro-3-(thiomorpholinomethyl)benzonitrile (CAS 1042783-59-4)
- Ethyl 2-(3-((2-hydroxyethyl)(methyl)amino)propanamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 356586-73-7)
- 4,5-Dibromo-2H-1,2,3-triazol-2-amine (CAS 181124-72-1)
- Hypaconine (CAS 63238-68-6)
- Tirzepatide Impurity 33 (CAS CATO-C4X-324033)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com