Chlorpromazine EP Impurity C HCl CAS 53-60-1
| CAS No. | 53-60-1 |
| Molecular Formula | C17H20N2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 320.88 g/mol gives Chlorpromazine EP Impurity C HCl distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Chlorpromazine EP Impurity C HCl (CAS 53-60-1, C17H20N2SHCl) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Chlorpromazine EP Impurity C HCl (C17H20N2SHCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Chlorpromazine EP Impurity C HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H20N2S HCl |
| Molecular Weight | 320.88 g/mol |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorpromazine Standards
- Chlorpromazine N-Oxide Sulfoxide (CAS 10404-90-7)
- Chlorpromazine EP Impurity D (CAS 1225-64-5)
- Chlorpromazine-D6 hydrochloride (CAS 1228182-46-4)
- Chlorpromazine-d6 Oxalate (N,N-dimethyl-d6) (CAS 1276197-23-9)
- Chlorpromazine-13C,d3 Hydrochloride (CAS 1329612-87-4)
- Chlorpromazine Sulphoxide N-Oxide Maleate (CAS 150111-59-4)
- Chlorpromazine impurity 18 HCl (CAS 15502-93-9)
- Chlorpromazine Impurity 12 (CAS 1672-76-0)
Recommended Standards
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- 3-(2-Bromoethyl)-4-methylpyridine (CAS 1520125-88-5)
- 7-Bromo-4-methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole (CAS 1072811-22-3)
- (5S)-isopropyl 2-acetamido-6-amino-5-(2,3-difluorophenyl)hexanoate (CAS 1254841-08-1)
- (4-Iodo-1H-pyrrol-2-yl)(morpholino)methanone (CAS 1706448-49-8)
- 1-(2-Cyclopropyl-5,6,7,8-tetrahydroquinazolin-4-yl)pyrrolidine-3-carboxylic acid (CAS 1708268-60-3)
- Fragment-[3-31]-Semaglutide (CAS CATO-C4X-2226113)
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