Trazodone Impurity 85 CAS CATO-C4X-177285
| CAS No. | CATO-C4X-177285 |
| Molecular Formula | C18H20Cl2N4O |
| Molecular Weight | 379.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Trazodone Impurity 85.
Trazodone Impurity 85 (CAS CATO-C4X-177285) is a certified pharmaceutical impurity reference standard with the molecular formula C18H20Cl2N4O and a molecular weight of 379.28 g/mol.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Trazodone Impurity 85 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 379.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Trazodone Impurity 85 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H20Cl2N4O |
| Molecular Weight | 379.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Trazodone Standards
- Trazodone EP Impurity C (CAS 157072-19-0)
- Trazodone Hydrochloride EP Impurity M (CAS 157072-18-9 (cation form))
- Trazodone impurity 47 (CAS CATO-C4X-177247)
- Trazodone Impurity 58 (CAS 157072-20-3)
- Trazodone (CAS 19794-93-5)
- Trazodone Impurity 110 (CAS CATO-C4X-1772110)
- Trazodone EP Impurity A (CAS 55290-68-1)
- Trazodone Impurity 7 (CAS 53818-10-3)
Recommended Standards
- 2-(3,4-dichlorophenyl)-1-[4-(4-methoxyphenyl)piperazino]-1-ethanone 746633-16-9 KS-00003DU8 (CAS 746633-16-9)
- Pyraziflumid (CAS 942515-63-1)
- n-[4-chloro-3-(3-chloropropyl)-5-formyl-2,3-dihydro-1,3-thiazol-2-ylidene]benzenesulfonamide (CAS 723320-46-5)
- 2,2,2-Trifluoro-N-((E)-3-(1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)allyl)acetamide (CAS 115794-55-3)
- Belumosudil Impurity 47 (CAS 3084112-89-7)
- Suzetrigine Impurity 19 (CAS CATO-C4X-336919)
- Phytomenadione/Vitamin K1 Impurity 113 (CAS CATO-C4X-2207113)
- 1-(Tert-butyl) 4-ethyl 4-propylpiperidine-1,4-dicarboxylate (CAS 1033819-09-8)
- Methyl 2-O-Allyl-3,4-di-O-benzyl-α-D-mannopyranoside (CAS 210297-56-6)
- 3-(2-Bromo-4,5-dimethoxyphenyl)propanenitrile (CAS 35249-62-8)
- 2-((5H-[1,2,4]Triazino[5,6-b]indol-3-yl)thio)-N-(3-nitrophenyl)acetamide (CAS 332157-61-6)
- Ethyl 2-morpholinoquinoline-4-carboxylate (CAS 7147-97-9)
- N-(3-Aminophenyl)methanesulfonamide hydrochloride (CAS 57005-05-7)
- Uremic Pentapeptide (CAS 71494-20-7)
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