Trazodone EP Impurity A CAS 55290-68-1
| CAS No. | 55290-68-1 |
| Molecular Formula | C19H22ClN5O2 |
| Molecular Weight | 387.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Trazodone EP Impurity A is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Trazodone EP Impurity A (CAS 55290-68-1), a certified reference material (molecular formula C19H22ClN5O2, MW 387.86 g/mol) for analytical method development and quality control.
Structurally, Trazodone EP Impurity A (C19H22ClN5O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 387.86 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), Trazodone EP Impurity A meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H22ClN5O2 |
| Molecular Weight | 387.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Trazodone Standards
- Trazodone Impurity 110 (CAS CATO-C4X-1772110)
- Trazodone Impurity 7 (CAS 53818-10-3)
- Trazodone impurity 62 (CAS CATO-C4X-177262)
- Trazodone Impurity 85 (CAS CATO-C4X-177285)
- Trazodone EP Impurity E (CAS 1346599-35-6)
- Trazodone Impurity 108 (CAS CATO-C4X-1772108)
- Trazodone EP Impurity C (CAS 157072-19-0)
- Trazodone Hydrochloride EP Impurity M (CAS 157072-18-9 (cation form))
Recommended Standards
- N-(benzo[d][1,3]dioxol-5-yl)-2-(4-(5-chloro-2-methylphenyl)piperazin-1-yl)acetamide (CAS 499197-54-5)
- Z-Dimethomorph (CAS 113210-98-3)
- N-(2-(4-(4-chlorophenyl)piperazin-1-yl)-2-oxoethyl)-4-methoxybenzamide (CAS 338419-58-2)
- Dimethomorph (CAS 110488-70-5)
- 2-Amino-3-(quinolin-2-yl)propan-1-ol (CAS 1340447-76-8)
- 1417AF 878436-89-6 C19H15N3O3 {2-[(Quinolin-8-yloxy)methyl]-1H-benzimidazol-1-yl}acetic acid (CAS 878436-89-6)
- 3-Chloro-6-fluoro-5-(trifluoromethyl)pyridin-2-amine (CAS 188555-38-6)
- 1-ethyl-N,N-dimethyl-2-oxo-2,3-dihydro-1H-benzimidazole-5-sulfonamide (CAS 950061-09-3)
- N4-(2,5-Dimethoxyphenyl)-N2,N2-dimethyl-L-asparagine (CAS 1026765-90-1)
- 2-(1,1-Difluoroethyl)pyridine (CAS 114468-02-9)
- 2-Bromo-4-butyl-1-chlorobenzene (CAS 1160574-95-7)
- 77299-63-9 LDBBA Lithium diisobutyl-tert-butoxyaluminum hydride solution (CAS 77299-63-9)
- 5-(2-Chloroethyl)thiazol-2-amine hydrochloride (CAS 105773-90-8)
- D-Pro37-Tirzepatide (CAS CATO-CPTD788902)
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