Olaparib Impurity 80 CAS 4122-56-9
| CAS No. | 4122-56-9 |
| Molecular Formula | C9H8O3 |
| Molecular Weight | 164.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Olaparib Impurity 80 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Olaparib Impurity 80 (CAS 4122-56-9, C9H8O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Olaparib Impurity 80 (C9H8O3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C9H8O3 |
| Molecular Weight | 164.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Olaparib Standards
- Olaparib Impurity 60 (CAS CATO-C4X-113560)
- Olaparib Impurity 81 (CAS 4122-57-0)
- Olaparib Impurity 73 (CAS 164149-28-4)
- Olaparib impurity 144 (CAS CATO-C4X-1135144)
- Olaparib Impurity 77 (CAS 1937362-45-2)
- Olaparib Impurity 33 (CAS 550363-85-4)
- Olaparib Impurity 104 (CAS 545348-09-2)
- Olaparib Impurity 64 (CAS 155295-47-9)
Recommended Standards
- Esomeprazole Impurity 32 (CAS 2080-75-3)
- Isavuconazole Impurity 206 (CAS CATO-C4X-1236206)
- 3,4-Methylenedioxyacetophenone (CAS 3162-29-6)
- Isavuconazole Impurity 3 (CAS 2734004-61-4)
- Methotrexate impurity 56 (CAS CATO-C4X-115456)
- Trazodone Impurity 74 HCl (CAS 66158-98-3)
- Avanafil Impurity 133 (CAS 1508194-63-5)
- (S)-4-(4-(Benzyloxy)phenyl)-3-((tert-butoxycarbonyl)amino)butanoic acid (CAS 126825-16-9)
- (2R,3R,4S,5S,6R)-2-Phenethoxy-6-((((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)methyl)tetrahydro-2H-pyran-3,4,5-triol (CAS 129932-48-5)
- 6-(p-Tolyl)pyridazine-3-thiol (CAS 70420-98-3)
- 3-O, N4-Diacetyl-2-deoxycytidine (CAS 70284-47-8)
- 5-O-[Bis(4-methoxyphenyl)phenylmethyl]-2-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)guanosine (CAS 251647-50-4)
- Elmycin A (CAS 128061-13-2)
- Semaglutide impurity 200 (CAS CATO-C4X-2226200)
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