4-Chloro-1-methylpyridin-2(1H)-one CAS 53937-04-5
| CAS No. | 53937-04-5 |
| Molecular Formula | C6H6ClNO |
| Molecular Weight | 143.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Chloro-1-methylpyridin-2(1H)-one.
CATO supplies 4-Chloro-1-methylpyridin-2(1H)-one (CAS 53937-04-5), a certified reference material (molecular formula C6H6ClNO, MW 143.57 g/mol) for analytical method development and quality control.
Owing to an amide group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, 4-Chloro-1-methylpyridin-2(1H)-one is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 143.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Chloro-1-methylpyridin-2(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H6ClNO |
| Molecular Weight | 143.57 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 5-Chloro-6-methylpyridin-2-ol (CAS 103997-23-5)
- N-(3-Chloro-phenyl)hydroxylamine (CAS 10468-17-4)
- (5-Chloro pyrazin-2-yl) Methanamine (CAS 1060814-53-0)
- 4-Chloro-3-methylpyridine 1-Oxide (CAS 1073-34-3)
- 2-Chloro-3-hydrazinylpyridine (CAS 117087-45-3)
- 5-Chloro-2-methylpyridin-4(1H)-one (CAS 1196157-19-3)
- 2-Chloro-1-(1H-pyrrol-3-yl)ethanone (CAS 122450-28-6)
- 3-Chloro-2-methylpyridin-4-ol (CAS 1227499-23-1)
Recommended Standards
- 4,5-Diamino-2-chloropyridine (CAS 89182-17-2)
- 4-Chloro-2-hydrazinylpyridine (CAS 364757-36-8)
- 4-(Chloromethyl)pyridine 1-oxide (CAS 70258-17-2)
- 4-Chloro-2-methoxypyridine (CAS 72141-44-7)
- Neoline (CAS 466-26-2)
- 2-Chloro-5-fluoro-3-(trifluoromethyl)pyridine (CAS 72587-20-3)
- 2-(6-Amino-5-(chloromethyl)-4-(difluoromethyl)pyridin-3-yl)acetic acid (CAS 1806904-30-2)
- (2R,3R,4S,5R,6R)-2-ethoxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (CAS 18997-88-1)
- Ethyl 2-chloro-6-cyanonicotinate (CAS 130879-38-8)
- (S)-2-(3-Hydroxypyrrolidin-1-yl)-N-(2,2,2-trifluoroethyl)acetamide (CAS 1280928-21-3)
- 2-(2-Amino-5-(difluoromethyl)-4-fluoropyridin-3-yl)acetic acid (CAS 1806812-74-7)
- Ibuprofen impurity 137 (CAS CATO-C4X-1082137)
- 5,5-Difluoro-5,8-dihydro-6H-pyrano[3,4-d]pyrimidin-2-amine (CAS 1391733-01-9)
- [Ser]8-Acetylated Semaglutide (CAS CATO-C4X-2226218)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com