Dasatinib Impurity 12 CAS 62077-27-4
| CAS No. | 62077-27-4 |
| Molecular Formula | C7H7Cl2N |
| Molecular Weight | 176.04 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Dasatinib Impurity 12.
As a process- or degradation-related impurity, Dasatinib Impurity 12 (CAS 62077-27-4, C7H7Cl2N) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrile group, chlorine substitution, an aromatic ring system, Dasatinib Impurity 12 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 176.04 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Dasatinib Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H7Cl2N |
| Molecular Weight | 176.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Dasatinib Standards
Recommended Standards
- Lansoprazole Impurity 68 (CAS 168167-48-4)
- 4-bromo-2,2-dimethylbutanenitrile (CAS 1240955-62-7)
- Rupatadine impurity 9 (CAS 41711-38-0)
- 4-bromo-3,3-dimethylbutanenitrile (CAS 129415-93-6)
- Epristeride Impurity 6 (CAS CATO-C4X-30086)
- Bisoprolol Impurity 83 (CAS CATO-C4X-124783)
- Valsartan Gene Toxin Impurity 1 (CAS 62-75-9)
- 2-(3-(Difluoromethoxy)-4-methoxyphenyl)ethanethioamide (CAS 1193389-41-1)
- (4-Bromo-2-fluoro-5-methylphenyl)boronic acid (CAS 677777-57-0)
- 4,6-dimethoxypyrimidine-5-carboxylic acid (CAS 4319-93-1)
- 1-(4-Fluoro-2-(methylsulfonyl)phenyl)piperidine-4-carboxamide (CAS 914637-65-3)
- 5-Chloro-2-methylisoindoline-1,3-dione (CAS 63197-17-1)
- 6-chloro-4-hydroxy-3-Quinolinecarbonitrile (CAS 61338-16-7)
- Neuropeptide GE (CAS 134748-04-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com