Dasatinib Impurity 42 CAS 1780-26-3
| CAS No. | 1780-26-3 |
| Molecular Formula | C5H4Cl2N2 |
| Molecular Weight | 163.00 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies Dasatinib Impurity 42 (CAS 1780-26-3), a pharmacopoeial impurity reference standard (molecular formula C5H4Cl2N2, MW 163.00 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C5H4Cl2N2, Dasatinib Impurity 42 contains a nitrile group, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 163.00 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C5H4Cl2N2 |
| Molecular Weight | 163.00 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dasatinib Standards
Recommended Standards
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- 4-(4-(Ethoxycarbonyl)piperidin-1-yl)-4-oxobutanoic acid (CAS 737794-19-3)
- 1-(2-Chlorothiazol-5-yl)-N-(piperidin-4-ylmethyl)methanamine hydrochloride (CAS 1261234-99-4)
- Methyl (5-allyl-3,3-dimethyl-4-oxo-2,3,4,5-tetrahydrobenzo[b][1,4]oxazepin-8-yl)carbamate (CAS 921565-35-7)
- Peracetic Acid Solution (CAS 79-21-0)
- Semaglutide Impurity 137 (x TFA Salt) (CAS CATO-C4X-2226137)
Why CATO?
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