Pomalidomide Impurity 37 CAS 5466-84-2
| CAS No. | 5466-84-2 |
| Molecular Formula | C8H3NO5 |
| Molecular Weight | 193.11 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Pomalidomide Impurity 37 (C8H3NO5) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Pomalidomide Impurity 37 (CAS 5466-84-2), a pharmacopoeial impurity reference standard (molecular formula C8H3NO5, MW 193.11 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Pomalidomide Impurity 37 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H3NO5 |
| Molecular Weight | 193.11 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
Related Pomalidomide Standards
- Pomalidomide Impurity 36 (CAS 641-70-3)
- Pomalidomide Impurity 46 (CAS 944709-53-9)
- Pomalidomide Impurity 62 (CAS CATO-C4X-135462)
- Pomalidomide Impurity 7 (CAS 5434-21-9)
- Pomalidomide Impurity 31 (CAS 610-27-5)
- Pomalidomide Impurity 8 (CAS 603-11-2)
- Pomalidomide Impurity 47 (CAS 885278-16-0)
- Pomalidomide Impurity 3 (CAS 328-48-3)
Recommended Standards
- 1-Bromo-2,2-dimethylhexane (CAS 101419-70-9)
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- 4-(Bromomethyl)heptane (CAS 101654-29-9)
- 3-((Difluoromethoxy)methyl)isoxazole-4-carboxylic acid (CAS 2735654-47-2)
- Midazolam Impurity 15 (CAS 59468-73-4)
- Nadifloxacin Impurity 14 (CAS 458-11-7)
- Daptomycin Impurity 3 (CAS 883991-21-7)
- Acetylenebis(cyclopentadienyl)dinickel (CAS 52445-55-3)
- 2-Isopropylisonicotinic Acid (CAS 191535-55-4)
- 2-(3-Chlorophenyl)-5-nitro-1H-benzo[d]imidazole (CAS 1571-88-6)
- 3-(3,4-Dichlorophenyl)-2-sulfanyl-3,4-dihydroquinazolin-4-one (CAS 282729-77-5)
- Ethyl 4-bromo-3-isobutyl-1H-pyrazole-5-carboxylate (CAS 1354895-87-6)
- 1-Bromo-4-[(1E)-4-bromobut-1-en-1-yl]benzene (CAS 1190898-63-5)
- Delta-Sleep Inducing Peptide (CAS 62568-57-4)
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