Cefuroxime Axetil EP Impurity D CAS 55268-75-2
| CAS No. | 55268-75-2 |
| Molecular Formula | C16H16N4O8S |
| Molecular Weight | 424.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Cefuroxime Axetil EP Impurity D (CAS 55268-75-2) is a certified pharmaceutical impurity reference standard with the molecular formula C16H16N4O8S and a molecular weight of 424.39 g/mol.
The molecular framework of Cefuroxime Axetil EP Impurity D (C16H16N4O8S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Cefuroxime Axetil EP Impurity D under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H16N4O8S |
| Molecular Weight | 424.39 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Cefuroxime Standards
- Cefuroxime Impurity 13 (CAS 229499-08-5)
- Cefuroxime Sodium EP Impurity E (CAS 97232-97-8)
- Cefuroxime Sodium EP Impurity B (CAS 39685-31-9)
- Cefuroxime Sodium EP Impurity G (CAS 97232-98-9)
- Cefuroxime-d3 (CAS 1803240-98-3)
- Cefuroxime impurity 106 (CAS CATO-C4X-1245106)
- Cefuroxime Impurity 48 (CAS CATO-C4X-124548)
- Cefuroxime Impurity 49 (CAS CATO-C4X-124549)
Recommended Standards
- 6-(Dimethylamino)-9-(4-Methylbenzyl)-2-(Trifluoromethyl)-9H-Purine (CAS 117860-34-1)
- (6R,7S)-Cefuroxime Isomer (CAS CATO-C4X-124519)
- N-((2S,3R,4R,5R,6R)-2-(((2R,3S,4R,5R)-5-acetamido-1,2,4-trihydroxy-6-oxohexan-3-yl)oxy)-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-3-yl)acetamide (CAS 136198-41-9)
- 13-alpha-(21)-Epoxyeurycomanone (CAS 138809-10-6)
- Mosapride Impurity 39 (CAS CATO-C4X-104439)
- Nintedanib Impurity 150 (CAS CATO-C4X-1814150)
- Lurbinectedin Impurity 15 (CAS 2248127-59-3)
- 2-Methyl-4-(trifluoromethyl)-5-thiazolamine (CAS 958452-22-7)
- (R)-N-(2-Acetyl-5,12-dihydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracen-2-yl)acetamide (CAS 104319-02-0)
- Methyl N-(2-ethoxyphenyl)-N-(phenylsulfonyl)glycinate (CAS 358378-00-4)
- 1-(2,3,4,5,6-Pentamethylphenyl)ethan-1-one (CAS 2040-01-9)
- 2-Chloro-4-fluoro-6-methylphenylboronic acid (CAS 2121514-96-1)
- Fesoterodine Impurity 19 (CAS CATO-C4X-164419)
- Semaglutide impurity 215 (CAS CATO-C4X-2226215)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com