Cefuroxime Sodium EP Impurity B CAS 39685-31-9
| CAS No. | 39685-31-9 |
| Molecular Formula | C17H17N3O8S |
| Molecular Weight | 423.40 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Cefuroxime Sodium EP Impurity B under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Cefuroxime Sodium EP Impurity B (CAS 39685-31-9) is a certified pharmaceutical impurity reference standard with the molecular formula C17H17N3O8S and a molecular weight of 423.40 g/mol.
The molecular framework of Cefuroxime Sodium EP Impurity B (C17H17N3O8S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C17H17N3O8S |
| Molecular Weight | 423.40 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1968 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Cefuroxime Standards
- Cefuroxime Sodium EP Impurity G (CAS 97232-98-9)
- Cefuroxime Impurity 13 (CAS 229499-08-5)
- Cefuroxime Sodium EP Impurity E (CAS 97232-97-8)
- Cefuroxime Axetil EP Impurity D (CAS 55268-75-2)
- Cefuroxime-d3 (CAS 1803240-98-3)
- Cefuroxime Impurity 48 (CAS CATO-C4X-124548)
- Cefuroxime Impurity 49 (CAS CATO-C4X-124549)
- Cefuroxime impurity 106 (CAS CATO-C4X-1245106)
Recommended Standards
- 3,5-Bis((4-chlorobenzyl)thio)isothiazole-4-carbonitrile (CAS 252725-31-8)
- 2,6-Difluoro-N-(4-(((3-(trifluoromethyl)phenyl)thio)methyl)phenyl)benzamide (CAS 338398-64-4)
- Ceftizoxime Impurity 6 (CAS CATO-C4X-17936)
- 3-((4-Fluorophenyl)sulfonyl)-1-((4-(trifluoromethyl)phenyl)sulfonyl)azetidine (CAS 1448064-42-3)
- Ledipasvir Impurity 49 (CAS CATO-C4X-331349)
- Osimertinib Impurity 97 (CAS CATO-C4X-204597)
- Lefamulinum Impurity 37 (CAS CATO-C4X-304737)
- 5-((6-Ethyl-2,6-diazaspiro[3.3]Heptan-2-yl)methyl)pyridin-2-amine (CAS 2306275-88-5)
- Canagliflozin Impurity 29 (CAS CATO-C4X-112329)
- 2-Chloro-1-(3,4-dichlorophenyl)-2,2-difluoroethan-1-one (CAS 1352232-04-2)
- trans-tert-butyl 3-hydroxy-3-methylcyclobutylcarbamate (CAS 1363382-14-2)
- (Z)-Hex-3-en-1-yl formate (CAS 33467-73-1)
- (S)-3-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-4-(pyridin-4-yl)butanoic acid (CAS 270065-69-5)
- Semaglutide impound 212 (CAS CATO-C4X-2226212)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com