Nintedanib Impurity 150 CAS CATO-C4X-1814150
| CAS No. | CATO-C4X-1814150 |
| Molecular Formula | C10H11Cl3O3 |
| Molecular Weight | 285.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Nintedanib Impurity 150.
CATO supplies Nintedanib Impurity 150 (CAS CATO-C4X-1814150), a pharmacopoeial impurity reference standard (molecular formula C10H11Cl3O3, MW 285.55 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C10H11Cl3O3, Nintedanib Impurity 150 contains a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 285.55 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Nintedanib Impurity 150 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H11Cl3O3 |
| Molecular Weight | 285.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Nintedanib Standards
- Nintedanib Impurity 140 (CAS CATO-C4X-1814140)
- Nintedanib Impurity 151 (CAS CATO-C4X-1814151)
- Nintedanib Impurity 152 (CAS CATO-C4X-1814152)
- Nintedanib Impurity 153 (CAS CATO-C4X-1814153)
- Nintedanib Impurity 124 (CAS CATO-C4X-1814124)
- Nintedanib Nintedanib Impurity 88 (CAS CATO-C4X-181488)
- Nintedanib Impurity 108 (CAS CATO-C4X-1814110)
- Nintedanib Impurity 75 (CAS 1253768-91-0)
Recommended Standards
- 5-Bromo-6-chloro-N-methylpyridine-3-sulfonamide (CAS 622814-92-0)
- 5-Bromo-4-chloro-6-methyl-2-(methylsulfonyl)pyrimidine (CAS 98141-98-1)
- 3,3,4-Trichlorobenzophenone (CAS 812684-89-2)
- 6-Bromo-1-chloro-2-ethoxynaphthalene (CAS 1394291-31-6)
- Chlorpromazine Impurity 21 (CAS 68962-15-2)
- Brivaracetam Impurity 153 (CAS CATO-C4X-2007153)
- Minoxidil Impurity 71 (CAS CATO-C4X-170071)
- (R)-2-(2,5-dimethylphenyl)pyrrolidine (CAS 1212904-28-3)
- N-Methyl-N-(4-oxoquinazolin-3(4H)-yl)acetamide (CAS 60512-92-7)
- 5-(Azepan-1-yl)-2-(ethylsulfonyl)aniline (CAS 1220033-67-9)
- Bis(p-fluorophenyl)methylsilane (CAS 1893-48-7)
- 3-(2-Bromoethyl)-5-fluoro-1H-indole (CAS 127561-10-8)
- 6-((4-Chlorophenyl)sulfonyl)-2-(3-(2,5-dimethyl-1H-pyrrol-1-yl)thiophen-2-yl)-7-phenylpyrazolo[1,5-a]pyrimidine (CAS 861209-15-6)
- D-β-Asp15-Tirzepatide (CAS CATO-CPTD788930)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com