Vancomycin EP Impurity B CAS 555598-85-1
| CAS No. | 555598-85-1 |
| Molecular Formula | C66H74Cl2N8O25 |
| Molecular Weight | 1450.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Vancomycin EP Impurity B (CAS 555598-85-1), a pharmacopoeial impurity reference standard (molecular formula C66H74Cl2N8O25, MW 1450.24 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Vancomycin EP Impurity B (C66H74Cl2N8O25) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 33.0, corresponding to approximately 33 ring(s) or double-bond equivalent(s). With a molecular weight of 1450.24 g/mol, it falls into the high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Vancomycin EP Impurity B under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C66H74Cl2N8O25 |
| Molecular Weight | 1450.24 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 33.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 8 |
Related Vancomycin Standards
- Vancomycin EP Impurity L (CAS 79517-31-0)
- Vancomycin EP Impurity E (CAS 55598-85-1)
- Vancomycin EP Impurity I (CAS CATO-C4X-177510)
- Vancomycin EP Impurity J (CAS 2416251-24-4)
- Vancomycin Impurity M (CAS CATO-C4X-177522)
- Vancomycin impurity 26 (CAS CATO-C4X-177526)
- Vancomycin impurity 28 (CAS CATO-C4X-177528)
- Vancomycin (CAS 1404-90-6)
Recommended Standards
- 9,12-Octadecadienoic acid (9Z,12Z)-, (2R,14R)-5,8,11-trihydroxy-5,11-dioxido-4,6,10,12-tetraoxa-5,11-diphosphapentadecane-1,2,14,15-tetrayl ester (CAS 152595-52-3)
- Casein kinase II peptide Substrate (CAS 154444-98-1)
- IHIC-4F/F6IC (CAS 2234282-80-3)
- Acetyl decapeptide-3 (CAS 935288-50-9)
- Miglitol Impurity A (CAS 1370331-33-1)
- Lenvatinib Impurity 52 (CAS CATO-C4X-114052)
- Azilsartan Impurity 61 (CAS 856414-36-3)
- 3-((4-(Trifluoromethoxy)phenyl)amino)propanenitrile (CAS 130997-77-2)
- Methyl 2-bromo-6-(difluoromethyl)benzoate (CAS 1806632-94-9)
- (1R,2R)-N1,N1-Dibenzylcyclohexane-1,2-diamine (CAS 593284-15-2)
- 3-Benzyl-3-azabicyclo[3.2.0]heptane-1-carboxylic acid (CAS 1821237-72-2)
- 1-(5-Bromo-2-methoxyphenyl)-2,2,2-trifluoroethan-1-ol (CAS 1169882-53-4)
- 1-Bromo-4-(ethylsulfinyl)benzene (CAS 30506-29-7)
- Cholecystokinin Octapeptide free acid (desulfated) (H-2075.0001) (CAS 103974-46-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com