Vancomycin impurity 28 CAS CATO-C4X-177528
| CAS No. | CATO-C4X-177528 |
| Molecular Formula | C66H75Cl2N9O24 |
| Molecular Weight | 1449.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Vancomycin impurity 28 (C66H75Cl2N9O24) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Vancomycin impurity 28 (CAS CATO-C4X-177528), a pharmacopoeial impurity reference standard (molecular formula C66H75Cl2N9O24, MW 1449.25 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Vancomycin impurity 28 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C66H75Cl2N9O24 |
| Molecular Weight | 1449.25 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 33.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 9 |
Related Vancomycin Standards
- Vancomycin EP Impurity I (CAS CATO-C4X-177510)
- Vancomycin EP Impurity J (CAS 2416251-24-4)
- Vancomycin Impurity M (CAS CATO-C4X-177522)
- Vancomycin impurity 26 (CAS CATO-C4X-177526)
- Vancomycin (CAS 1404-90-6)
- Vancomycin EP Impurity L (CAS 79517-31-0)
- Vancomycin EP Impurity B (CAS 555598-85-1)
- Vancomycin EP Impurity E (CAS 55598-85-1)
Recommended Standards
- Mogroside VI (CAS 89590-98-7)
- IHIC-4F/F6IC (CAS 2234282-80-3)
- 9,12-Octadecadienoic acid (9Z,12Z)-, (2R,14R)-5,8,11-trihydroxy-5,11-dioxido-4,6,10,12-tetraoxa-5,11-diphosphapentadecane-1,2,14,15-tetrayl ester (CAS 152595-52-3)
- Chloroorienticin B (CAS 118373-81-2)
- Ilaprazole Impurity 225 (CAS CATO-C4X-1130225)
- Lurasidone Impurity 72 (CAS CATO-C4X-102872)
- Latamoxef Impurity 18 (CAS CATO-C4X-179818)
- 4-(Piperazin-1-yl)tetrahydro-2h-thiopyran-4-carboxamide (CAS 1247501-30-9)
- 1-Methyl-1,2,3,4-tetrahydroquinoline-6-carbonyl chloride (CAS 32565-01-8)
- (3aS,3'aS,8aR,8'aR)-2,2'-Ethylidenebis[3a,8a-dihydro-8H-indeno[1,2-d]oxazole] (CAS 1091605-95-6)
- 4-Fluoro-3-propoxy-5-(trifluoromethyl)phenylboronic acid (CAS 2377605-72-4)
- N-Me-Val-OMe · HCl (CAS 3339-44-4)
- 2-Chloro-N-(4-methoxy-phenyl)-N-[(4-methoxy-phenylcarbamoyl)-methyl]-acetamide (CAS 1092295-00-5)
- Tirzepatide Impurity 45 (CAS CATO-C4X-324045)
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