Vancomycin EP Impurity E CAS 55598-85-1
| CAS No. | 55598-85-1 |
| Molecular Formula | C66H74Cl2N8O25 |
| Molecular Weight | 1450.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Vancomycin EP Impurity E (CAS 55598-85-1) is a certified pharmaceutical impurity reference standard with the molecular formula C66H74Cl2N8O25 and a molecular weight of 1450.24 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Vancomycin EP Impurity E is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 1450.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Vancomycin EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C66H74Cl2N8O25 |
| Molecular Weight | 1450.24 g/mol |
| Purity | >90% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 33.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1972 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 8 |
Related Vancomycin Standards
- Vancomycin EP Impurity L (CAS 79517-31-0)
- Vancomycin EP Impurity B (CAS 555598-85-1)
- Vancomycin EP Impurity I (CAS CATO-C4X-177510)
- Vancomycin EP Impurity J (CAS 2416251-24-4)
- Vancomycin Impurity M (CAS CATO-C4X-177522)
- Vancomycin impurity 26 (CAS CATO-C4X-177526)
- Vancomycin impurity 28 (CAS CATO-C4X-177528)
- Vancomycin (CAS 1404-90-6)
Recommended Standards
- Casein kinase II peptide Substrate (CAS 154444-98-1)
- Acetyl decapeptide-3 (CAS 935288-50-9)
- 9,12-Octadecadienoic acid (9Z,12Z)-, (2R,14R)-5,8,11-trihydroxy-5,11-dioxido-4,6,10,12-tetraoxa-5,11-diphosphapentadecane-1,2,14,15-tetrayl ester (CAS 152595-52-3)
- 4,4'-Bis[bis(2,3,4,5,6-pentachlorophenyl)methyl]-2,2',3,3',5,5',6,6'-octachloro-1,1'-biphenyl (CAS 33399-69-8)
- Lomustine Impurity 3 (CAS CATO-C4X-22763)
- Biapenem Impurity 23 (CAS CATO-C4X-227323)
- Cefaclor Impurity 56 (CAS CATO-C4X-127056)
- N-(Amino-PEG4)-N-bis(PEG4-Boc) (CAS 2093153-97-8)
- 4-((4-Formylphenoxy)methyl)benzonitrile (CAS 109702-08-1)
- 3-(2-Oxo-3-(trifluoromethyl)pyridin-1(2H)-yl)propanethioamide (CAS 265314-18-9)
- (4S)-4-(Adamantan-1-yl)-2-(2-(diphenylphosphanyl)phenyl)-4,5-dihydrooxazole (CAS 944836-03-7)
- 2-[4-(2-Hydroxyethyl)-1-Piperazinyl]Ethanesulfonic Acid (CAS 7365-45-9)
- 1-methyl-2,3-dihydro-1H-inden-2-one (CAS 35587-60-1)
- Semaglutide Impurity 5 (CAS 23406-82-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com