Sunitinib Impurity 16 CAS 56341-41-4
| CAS No. | 56341-41-4 |
| Molecular Formula | C8H6FNO |
| Molecular Weight | 151.14 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 151.14 g/mol gives Sunitinib Impurity 16 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Sunitinib Impurity 16 (CAS 56341-41-4), a pharmacopoeial impurity reference standard (molecular formula C8H6FNO, MW 151.14 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Sunitinib Impurity 16 (C8H6FNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6FNO |
| Molecular Weight | 151.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Sunitinib Standards
- Sunitinib Impurity 46 (CAS 138343-94-9)
- Sunitinib Impurity 47 (CAS 56341-39-0)
- Sunitinib Impurity 48 (CAS 71294-03-6)
- Sunitinib Impurity 87 (CAS 1032268-12-4)
- Sunitinib Impurity 62 (CAS CATO-C4X-133362)
- Sunitinib Impurity 86 (CAS 90433-88-8)
- Sunitinib Impurity 4 (CAS 17106-13-7)
- Sunitinib Impurity 45 (CAS 443-69-6)
Recommended Standards
- Olaparib Impurity 67 (CAS 227609-85-0)
- 62284-30-4 1-(Azidomethyl)-2-fluorobenzene DTXSID10611949 (CAS 62284-30-4)
- 202480-69-1 D-[2-2h]ribose (CAS 202480-69-1)
- D-Xylose-2-C-d (CAS 288846-91-3)
- Cefotaxime Impurity 46 (CAS 689293-67-2)
- Cefotiam Impurity 46 (CAS CATO-C4X-120446)
- Rapamycin Impurity 24 (CAS CATO-C4X-174624)
- (3-Methylthiophen-2-yl)(phenyl)methanone (CAS 56004-62-7)
- Ramosetron impurity 29 (CAS CATO-C4X-118229)
- (2S)-N-Methoxy-N,2-dimethylhexanamide-d3 (CAS 1330165-35-9)
- Sofosbuvir Impurity 8 (CAS 1910099-11-4)
- 2-(1-Hydroxy-1-Methylethyl)-4-Methoxy-7H-Furo[3,2-G][1]benzopyran-7-One (CAS 54087-32-0)
- 2-(7,8-Dimethoxy-4-methyl-2-oxo-2h-chromen-3-yl)acetic acid (CAS 855287-75-1)
- Semaglutide Impurity 21(HO-Ste-L-γGlu-AEEA-AEEA-OH) (CAS 1335440-44-2)
Why CATO?
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