Avatrombopag CAS 570406-98-3
| CAS No. | 570406-98-3 |
| Molecular Formula | C29H34Cl2N6O3S2 |
| Molecular Weight | 649.65 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Avatrombopag (C29H34Cl2N6O3S2) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Avatrombopag (CAS 570406-98-3) is a high-purity analytical reference standard with the molecular formula C29H34Cl2N6O3S2 and a molecular weight of 649.65 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C29H34Cl2N6O3S2 |
| Molecular Weight | 649.65 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1984 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 2 |
Related Avatrombopag Standards
- Avatrombopag Impurity 121 (CAS CATO-C4X-2234121)
- Avatrombopag impurity 136 (CAS CATO-C4X-2234136)
- Avatrombopag Impurity 3 (CAS CATO-C4X-22343)
- Avatrombopag Impurity 58 (CAS CATO-C4X-223458)
- Avatrombopag Impurity 8 (CAS CATO-C4X-22348)
- Avatrombopag Impurity 142 (CAS CATO-C4X-2234142)
- Avatrombopag Impurity 100 (CAS CATO-C4X-2234100)
- Avatrombopag Impurity 45 (CAS CATO-C4X-223445)
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