Avatrombopag Impurity 121 CAS CATO-C4X-2234121
| CAS No. | CATO-C4X-2234121 |
| Molecular Formula | C29H34Cl2N6O3S2 |
| Molecular Weight | 649.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Avatrombopag Impurity 121 is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Avatrombopag Impurity 121 (CAS CATO-C4X-2234121) is a certified pharmaceutical impurity reference standard with the molecular formula C29H34Cl2N6O3S2 and a molecular weight of 649.65 g/mol.
Avatrombopag Impurity 121 (C29H34Cl2N6O3S2) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Avatrombopag Impurity 121 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C29H34Cl2N6O3S2 |
| Molecular Weight | 649.65 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 2 |
Related Avatrombopag Standards
- Avatrombopag impurity 136 (CAS CATO-C4X-2234136)
- Avatrombopag (CAS 570406-98-3)
- Avatrombopag Impurity 3 (CAS CATO-C4X-22343)
- Avatrombopag Impurity 58 (CAS CATO-C4X-223458)
- Avatrombopag Impurity 8 (CAS CATO-C4X-22348)
- Avatrombopag Impurity 142 (CAS CATO-C4X-2234142)
- Avatrombopag Impurity 100 (CAS CATO-C4X-2234100)
- Avatrombopag Impurity 45 (CAS CATO-C4X-223445)
Recommended Standards
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- Benidipine Impurity 55 (CAS CATO-C4X-112055)
- 5-[3-(propan-2-yl)phenyl]furan-2-carboxylic acid (CAS 1094267-53-4)
- 3-(Methoxycarbonyl)-1-methyl-4-nitro-1H-pyrazole-5-carboxylic acid (CAS 159427-62-0)
- Tert-butyl 2-(2-(4-chlorophenyl)-1-((furan-2-ylmethyl)imino)ethyl)hydrazine-1-carboxylate (CAS 1053657-85-4)
- 5-Bromo-2-chloro-4-methylpyrimidine (CAS 633328-95-7)
- 3,4-Diethyl 2-amino-5-methylfuran-3,4-dicarboxylate (CAS 91248-60-1)
- 3-Phenylpicolinic acid (CAS 103863-15-6)
- D-Pro37-Tirzepatide (CAS CATO-CPTD788902)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com