Avatrombopag impurity 136 CAS CATO-C4X-2234136

Description

The occurrence of Avatrombopag impurity 136 is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies Avatrombopag impurity 136 (CAS CATO-C4X-2234136), a pharmacopoeial impurity reference standard (molecular formula C29H34Cl2N6O3S2, MW 649.65 g/mol) used for the identification and quantification of trace impurities in APIs.

Structurally, Avatrombopag impurity 136 (C29H34Cl2N6O3S2) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 649.65 g/mol, it falls into the high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.

CATO manufactures Avatrombopag impurity 136 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

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