Dimenhydrinate EP Impurity K CAS 574-42-5
| CAS No. | 574-42-5 |
| Molecular Formula | C26H22O |
| Molecular Weight | 350.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Dimenhydrinate EP Impurity K under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Dimenhydrinate EP Impurity K (CAS 574-42-5, C26H22O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Dimenhydrinate EP Impurity K (C26H22O) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C26H22O |
| Molecular Weight | 350.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Dimenhydrinate Standards
- Dimenhydrinate Impurity N4 (CAS 1797911-12-6)
- Dimenhydrinate Impurity C2 (CAS 2212-35-3)
- Dimenhydrinate Impurity 4 (CAS 33120-34-2)
- Dimenhydrinate EP Impurity E (CAS 4921-49-7)
- Dimenhydrinate Impurity(8-chloro-1-methyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione) (CAS 6136-36-3)
- Dimenhydrinate EP Impurity I (CAS 91-01-0)
- Dimenhydrinate EP Impurity A (CAS 58-55-9)
- Dimenhydrinate Impurity 6 (CAS 14177-81-2)
Recommended Standards
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- Pentyl cinnamate (CAS 3487-99-8)
- Metixene EP Impurity A (CAS 261-31-4)
- 2-((3-Chlorophenyl)amino)-5-methylthiazole-4-carboxylic acid (CAS 1553413-00-5)
- 4-Hydroxyquinoline-7-carboxaldehyde (CAS 1261490-52-1)
- D-Ser12-Semaglutide (CAS CATO-C4X-2226240)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com