Dimenhydrinate EP Impurity A CAS 58-55-9
| CAS No. | 58-55-9 |
| Molecular Formula | C7H8N4O2 |
| Molecular Weight | 180.16 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Dimenhydrinate EP Impurity A (CAS 58-55-9) is a certified pharmaceutical impurity reference standard with the molecular formula C7H8N4O2 and a molecular weight of 180.16 g/mol.
The molecular framework of Dimenhydrinate EP Impurity A (C7H8N4O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Dimenhydrinate EP Impurity A meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C7H8N4O2 |
| Molecular Weight | 180.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 4 |
Related Dimenhydrinate Standards
- Dimenhydrinate EP Impurity I (CAS 91-01-0)
- Dimenhydrinate Impurity(8-chloro-1-methyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione) (CAS 6136-36-3)
- Dimenhydrinate EP Impurity E (CAS 4921-49-7)
- Dimenhydrinate Impurity C2 (CAS 2212-35-3)
- Dimenhydrinate Impurity N4 (CAS 1797911-12-6)
- Dimenhydrinate EP Impurity K (CAS 574-42-5)
- Dimenhydrinate Impurity 6 (CAS 14177-81-2)
- Dimenhydrinate EP Impurity C Hydrate (CAS 5743-12-4)
Recommended Standards
- Caffeine Monohydrate EP Impurity F (CAS 611-59-6)
- Nafamostat Impurity 15 (CAS 6306-25-8)
- Acetaminophen Impurity 34 (CAS 146897-60-1)
- Aspirin Impurity 12 (CAS 13110-96-8)
- Diltiazem Impurity 33 (CAS CATO-C4X-136833)
- Drotaverine Impurity 28 (CAS CATO-C4X-243528)
- Peramivir Impurity 58 (CAS CATO-C4X-183358)
- Methyl 4-[(4-bromophenyl)sulfanyl]butanoate (CAS 1096302-47-4)
- 4-(Pyridin-3-yl)-5-(tetrahydro-2H-pyran-4-yl)-4H-1,2,4-triazole-3-thiol (CAS 1858250-40-4)
- 7-Chloro-4-fluoro-1H-indole-2,3-dione (CAS 1414958-28-3)
- Gadoteridol Impurity 18 (CAS 68516-39-2)
- Methyl 4-amino-2,3-difluorobenzoate (CAS 886497-08-1)
- (S)-2-(((Benzyloxy)carbonyl)amino)-3-fluoropropanoic acid (CAS 36369-37-6)
- Semaglutide Impurity 161 (x TFA Salt) (CAS CATO-C4X-2226161)
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