Diphenhydramine CAS 58-73-1
| CAS No. | 58-73-1 |
| Molecular Formula | C17H21NO |
| Molecular Weight | 255.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Diphenhydramine is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Diphenhydramine (CAS 58-73-1) is a high-purity analytical reference standard with the molecular formula C17H21NO and a molecular weight of 255.35 g/mol.
Structurally, Diphenhydramine (C17H21NO) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 255.35 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C17H21NO |
| Molecular Weight | 255.35 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Nitrogen Atoms | 1 |
Related Diphenhydramine Standards
- Diphenhydramine EP Impurity A(Dimenhydrinate EP Impurity F) (CAS 17471-10-2)
- Diphenhydramine EP Impurity B (CAS 19804-27-4)
- Diphenhydramine impurity 14 (CAS CATO-C4X-142414)
- Diphenhydramine N-Oxide (CAS 3922-74-5)
- Diphenhydramine Impurity 9 (CAS 26926-47-6)
- Diphenhydramine impurity 9 (CAS CATO-C4X-14249)
- Diphenhydramine impurity 17 (CAS 22808-17-9)
- Diphenhydramine impurity 18 (CAS 150556-79-9)
Recommended Standards
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- N,N'-((1S,2S)-1,2-Diphenylethane-1,2-diyl)dipicolinamide (CAS 135912-30-0)
- 7-Chloro-1-ethyl-3-methyl-1H-pyrazolo[4,3-d]pyrimidine (CAS 1092292-97-1)
- n-(Azetidin-3-yl)-3-chloro-4-methoxybenzenesulfonamide (CAS 1606784-65-9)
- 2-butyl-1H-imidazole-5-carbaldehyde (CAS 68282-49-5)
- Eledoisin Related Peptide (CAS 2990-43-4)
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