Dantrolene Impurity 3 CAS 58136-76-8
| CAS No. | 58136-76-8 |
| Molecular Formula | C12H10N4O4 |
| Molecular Weight | 274.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Dantrolene Impurity 3 (CAS 58136-76-8), a pharmacopoeial impurity reference standard (molecular formula C12H10N4O4, MW 274.23 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Dantrolene Impurity 3 (C12H10N4O4) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 274.23 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Dantrolene Impurity 3 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H10N4O4 |
| Molecular Weight | 274.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Nitrogen Atoms | 4 |
Related Dantrolene Standards
- Dantrolene Impurity 5 (CAS 14663-28-6)
- Dantrolene (CAS 7261-97-4)
- 13C3-Dantrolene (CAS 1185234-99-4)
- Dantrolene-d4 (CAS 7261-97-4 (unlabeled))
- Dantrolene Impurity 1 (CAS 7147-77-5)
- Dantrolene Related Compound B (CAS 57268-33-4)
- Dantrolene Impurity 2 (CAS CATO-C4X-27442)
- Dantrolene Impurity 5 (CAS 55227-60-6)
Recommended Standards
- Leflunomide EP Impurity B-d4 (Teriflunomide-d4) (CAS 1185240-22-5)
- Disperse Yellow 9 (CAS 6373-73-5)
- Leflunomide-d4 (CAS 1189987-23-2)
- (E)-3-(3-(4-Fluorophenyl)acryloyl)-4-hydroxy-6-methyl-2H-pyran-2-one (CAS 1006372-29-7)
- Biotin EP Impurity H (Mixture of Diastereomers) (CAS 2714810-33-8)
- Safinamide Impurity 31 (CAS 202825-43-2)
- Pemetrexed Impurity 43 (CAS 863767-87-7)
- tert-Butyl ((2-formyl-6-(trifluoromethyl)pyridin-4-yl)methyl)carbamate (CAS 1393572-85-4)
- (R)-4-(2-(1-Hydroxyethyl)imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H)-yl)cyclohexanone (CAS 1418199-15-1)
- 2-(4-(3,4-Dimethyl-2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzamido)acetic acid (CAS 83560-86-5)
- 144060-98-0 4-Methyl-2-(pyridin-4-yl)-1,3-thiazole-5-carboxylic acid DTXSID20363285 (CAS 144060-98-0)
- 6-Acetyl-4-methoxypicolinaldehyde (CAS 1393551-23-9)
- 3-alfa,5-beta-Tetrahydro Levonorgestrel (CAS 19351-16-7)
- Galanin-Like Peptide (human) trifluoroacetate salt (CAS 245114-99-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com