| CAS No. | 5949-29-1 |
| Molecular Formula | C6H8O7 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
CATO supplies Citric Acid Impurity 5 (CAS 5949-29-1), a pharmacopoeial impurity reference standard (molecular formula C6H8O7H2O, MW 210.14 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a carbohydrate-derived structure, Citric Acid Impurity 5 is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 210.14 g/mol — guide the selection of appropriate sample preparation and analytical techniques.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
| Molecular Formula | C6H8O7 H2O |
| Molecular Weight | 210.14 g/mol |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO, water |
| Stability | Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1958 |