Apixaban Impurity 57 CAS CATO-C4X-108857
| CAS No. | CATO-C4X-108857 |
| Molecular Formula | C21H18N4O6 |
| Molecular Weight | 422.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Apixaban Impurity 57 is closely related to a flavonoid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Apixaban Impurity 57 (CAS CATO-C4X-108857), a pharmacopoeial impurity reference standard (molecular formula C21H18N4O6, MW 422.39 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Apixaban Impurity 57 (C21H18N4O6) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Apixaban Impurity 57 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H18N4O6 |
| Molecular Weight | 422.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Apixaban Standards
- Apixaban Impurity 171 (CAS CATO-C4X-1088171)
- Apixaban Impurity 95 (CAS CATO-C4X-108895)
- Apixaban Impurity 73 (CAS CATO-C4X-108873)
- Apixaban Impurity 59 (CAS CATO-C4X-108859)
- Apixaban Impurity 149 (CAS CATO-C4X-1088149)
- Apixaban Impurity 181 (CAS CATO-C4X-1088181)
- Apixaban Impurity 133 (CAS CATO-C4X-1088133)
- Apixaban Impurity 44 (CAS 536759-91-8)
Recommended Standards
- CAS 948574-00-3 (CAS 948574-00-3)
- Fruquintinib Impurity 16 (CAS CATO-C4X-303716)
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- Opanixil (CAS 152939-42-9)
- Venlafaxine Impurity 27 (CAS 940297-06-3)
- Etomidate Impurity 75 (CAS 1567838-90-7)
- Ixazomib Impurity 25 (CAS CATO-C4X-126725)
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- Propargyl-PEG<SUB>2</SUB>-acid (CAS 1859379-85-3)
- 6-(Ethyl(methyl)amino)-4-methylnicotinonitrile (CAS 1355217-88-7)
- 4-(4-methoxyphenyl)-5-sulfanyl-8-thia-4,6-diazatricyclo[7.4.0.0²,⁷]trideca-1(9),2(7),5-trien-3-one (CAS 65234-02-8)
- Tert-butyl 4-((4-(trifluoromethyl)phenyl)amino)piperidine-1-carboxylate (CAS 401565-92-2)
- Methyl 4-(4-chlorophenyl)-1-methylpyrrolidine-3-carboxylate (CAS 1706459-58-6)
- Des-Ala35-Tirzepatide (CAS CATO-CPTD788939)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com