Norethindrone Impurity 23 (6-beta-Hydroxy-19-Norandrostenedione) CAS 5949-49-5
| CAS No. | 5949-49-5 |
| Molecular Formula | C18H24O3 |
| Molecular Weight | 288.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Norethindrone Impurity 23 (6-beta-Hydroxy-19-Norandrostenedione) (C18H24O3) contains a steroid core, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 288.38 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Norethindrone Impurity 23 (6-beta-Hydroxy-19-Norandrostenedione) (CAS 5949-49-5) is a certified pharmaceutical impurity reference standard with the molecular formula C18H24O3 and a molecular weight of 288.38 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Norethindrone Impurity 23 (6-beta-Hydroxy-19-Norandrostenedione) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H24O3 |
| Molecular Weight | 288.38 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Norethindrone Standards
- Norethindrone (CAS 68-22-4)
- Norethindrone Impurity 5 (CAS 16392-60-2)
- Norethindrone Impurity 6 (CAS 6424-05-1)
- Norethindrone Impurity 8 (CAS 25796-09-2)
- Norethindrone-D6 (CAS CATO-CCAD301120)
- 6-Oxo Norethindrone (CAS 67696-78-0)
- Norethindrone 6-alpha-Hydroxy Impurity (CAS 438244-33-8)
- Norethindrone Acetate (CAS 38673-38-0)
Recommended Standards
- N-Butyl-1-(4-ethylphenyl)-5-oxopyrrolidine-3-carboxamide (CAS 425606-85-5)
- Phenyldi-p-tolylmethanol (CAS 6266-56-4)
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- Psoracorylifol B (CAS 879290-98-9)
- Ceftazidime Impurity C07 (CAS 752152-44-6)
- Metoclopramide Impurity 67 (CAS CATO-C4X-141567)
- Deferiprone Impurity 12 (CAS CATO-C4X-304812)
- (3,4-Dimethylphenyl)(4-(morpholinomethyl)phenyl)methanone (CAS 898770-14-4)
- N,N-Dimethyl-4-(oxazolo[4,5-b]pyridin-2-yl)aniline (CAS 109055-38-1)
- 1-[(4-chlorophenyl)methyl]-1h-1,2,4-triazol-3-amine (CAS 147159-33-9)
- 1-(3-Bromopropyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione (Pentoxifylline impurity) (CAS 6493-10-3)
- Sk1-in-1 (CAS 1218816-71-7)
- Sonidegib diphosphate, 98% (HPLC) (CAS 1218778-77-8)
- Des-Ser34-Gly33Tirzepatide (CAS CATO-CPTD788941)
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