Norethindrone Impurity 5 CAS 16392-60-2
| CAS No. | 16392-60-2 |
| Molecular Formula | C20H30O2 |
| Molecular Weight | 302.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, a hydroxyl group, an ether linkage, Norethindrone Impurity 5 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 302.45 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies Norethindrone Impurity 5 (CAS 16392-60-2), a pharmacopoeial impurity reference standard (molecular formula C20H30O2, MW 302.45 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H30O2 |
| Molecular Weight | 302.45 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
Related Norethindrone Standards
- Norethindrone Impurity 6 (CAS 6424-05-1)
- Norethindrone Impurity 8 (CAS 25796-09-2)
- Norethindrone-D6 (CAS CATO-CCAD301120)
- Norethindrone (CAS 68-22-4)
- 6-Oxo Norethindrone (CAS 67696-78-0)
- Norethindrone 6-alpha-Hydroxy Impurity (CAS 438244-33-8)
- Norethindrone Impurity 23 (6-beta-Hydroxy-19-Norandrostenedione) (CAS 5949-49-5)
- Norethindrone Acetate (CAS 38673-38-0)
Recommended Standards
- 3-Methoxy-7α-methyl-estra-2,5(10)-dien-17β-ol (CAS 15506-02-2)
- 9-Cis-13,14-Dihydro Retinoic Acid (CAS 176019-01-5)
- 3,6,9-Trioxaeicos-19-en-1-ol (CAS 130727-45-6)
- 8,13(15)-Abietadienoic Acid (CAS 19402-33-6)
- Rosuvastatin Impurity 163 (CAS CATO-C4X-1169163)
- Emodepside Impurity 1 (CAS 133413-70-4)
- Tolvaptan Impurity 48 (CAS CATO-C4X-195548)
- Posaconazole Impurity N2 (CAS 183871-36-5)
- 1-Benzenesulfonyl-7-methyl-4-azaindole (CAS 1427503-71-6)
- Gadobutrol impurity 164 (CAS CATO-C4X-2120164)
- 2-(2,2,2-trifluoroethoxy)pyridin-4-amine (CAS 1247075-58-6)
- 7-bromo-3H,4H-pyrrolo[2,1-f][1,2,4]triazin-4-one (CAS 1370007-53-6)
- 2,2,5,5-Tetramethyltetrahydrofuran (CAS 15045-43-9)
- Semaglutide impurity 257 (CAS CATO-C4X-2226257)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com