2-chloro-7-methoxy-5-(propan-2-yl)-3,4-dihydroquinazolin-4-one CAS 601516-82-9

Purity 97%+In StockPharmaceutical Standards
CAS No.601516-82-9
Molecular FormulaC12H21ClN2O2
Molecular Weight260.76 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-chloro-7-methoxy-5-(propan-2-yl)-3,4-dihydroquinazolin-4-one CAS 601516-82-9 chemical structure

Description

The occurrence of 2-chloro-7-methoxy-5-(propan-2-yl)-3,4-dihydroquinazolin-4-one is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

2-chloro-7-methoxy-5-(propan-2-yl)-3,4-dihydroquinazolin-4-one (CAS 601516-82-9) is a high-purity analytical reference standard with the molecular formula C12H21ClN2O2 and a molecular weight of 260.76 g/mol.

2-chloro-7-methoxy-5-(propan-2-yl)-3,4-dihydroquinazolin-4-one (C12H21ClN2O2) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC12H21ClN2O2
Molecular Weight260.76 g/mol
AppearanceWhite to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1985
Halogen ContentCl-containing
Nitrogen Atoms2

Related chloro Standards

Recommended Standards

Why CATO?